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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 315 - 323 (9page)
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Foot-and-mouth disease (FMD) virus exists in seven serotypes and is known to be a highly contagious disease that is hard to eradicate from the world. The O, A, Asia1 and SAT2 serotypes commonly infected
cattle, sheep and goats during 2007~2009 throughout the world. In particular, the outbreak of the Asia1 serotype in China appeared in all areas from 2005 and is still present. Surprisingly, in 2009, Taiwan reported the first outbreak of the type O serotype since 2001. Then type A appeared in China for the first
time since the early 1960s. The virus shows a close relationship to the viruses from Southeast Asia suggesting one or more recent introductions into China in the OIE reports. Recently the subtype of A/Iran05
spread to nearby countries exhibiting genomic evolution. The use of molecular epidemiology is an important tool in understanding and consequently controlling the FMD virus. The phylogenetic analysis with VP1
gene was especially useful for molecular epidemiological studies and showed the same pattern which matches with serotype classification. This paper describes basic information about the disease, and the
serotype-specific characteristics and evolution to perform molecular epidemiological analysis. Furthermore, we show the importance of the genetic evolution on the FMD serotypes in global surveillance and
molecular epidemiology of FMD for outbreak investigation.
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참고문헌 (25)
참고문헌 신청
Aidaros HA / 2002 / Regional status and approaches to control and eradication of foot and mouth disease in the Middle East and North Africa / Rev Sci Tech 21 (3) : 451 ~ 458
Arias A / 2001 / Molecular intermediates of fitness gain of an RNA virus: characterization of a mutant spectrum by biological and molecular cloning / J Gen Virol 82 (Pt 5) :
Bachrach HL / 1968 / Foot-and-mouth disease / Annu Rev Microbiol 22 : 201 ~ 244
Baranowski E / 1998 / Multiple virulence determinants of foot-and-mouth disease virus in cell culture / J Virol 72 (8) : 6362 ~ 6372
Bastos AD / 2001 / Genetic heterogeneity of SAT-1 type foot-and-mouth disease viruses in southern Africa / Arch Virol 146 (8) : 1537 ~ 1551
Arias A / 2001 / Molecular intermediates of fitness gain of an RNA virus: characterization of a mutant spectrum by biological and molecular cloning / J Gen Virol 82 (Pt 5) :
Bachrach HL / 1968 / Foot-and-mouth disease / Annu Rev Microbiol 22 : 201 ~ 244
Baranowski E / 1998 / Multiple virulence determinants of foot-and-mouth disease virus in cell culture / J Virol 72 (8) : 6362 ~ 6372
Bastos AD / 2001 / Genetic heterogeneity of SAT-1 type foot-and-mouth disease viruses in southern Africa / Arch Virol 146 (8) : 1537 ~ 1551
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