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논문 기본 정보

자료유형
학술저널
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대한자기공명의과학회 Investigative Magnetic Resonance Imaging Investigative Magnetic Resonance Imaging 제13권 제1호
발행연도
2009.1
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74 - 80 (7page)

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Purpose : To evaluate the characteristic MR imaging findings of Langerhans cell histiocytosis (LCH) in the skull and to compare them with those of plain radiography and computed tomography. Materials and Methods : A total of 10 lesions in 9 patients (Age range; 5-42 years, Mean age; 18, all women) with Langerhans cell histiocytosis in the skull were included in our study. Nine lesions in nine patients were histologically confirmed by surgery or fine needle aspiration biopsy. All patients performed with MRI, and plain radiography and CT scan were done in 7 patients (8 lesions). Two experienced neuroradiologists reviewed the radiological examinations independently with attention to location, size, shape and nature of the lesions in the skull and compared the extent and extension of the lesions to adjacent structures. Results : The lesions were distributed in all of the skulls without predilection site. On MRI, the masses were shown as well-enhancing soft tissue masses (10/10) mainly in diploic spaces (8/10) with extension to scalp (9/10) and dura mater (7/10). Dural enhancement (7/10) and thickening (4/10) were seen. The largest diameter of the soft tissue masses ranged 1.1 cm to 6.8 cm, shaped as round (5/10) or oval (5/10). On CT scans, the lesions were presented as soft tissue masses involving diploic space (6/8) and scalp extension (7/8) were also well visualized. Although bony erosion or destruction was more clearly seen on CT rather than those of MRI, enhancement of soft tissue masses and dura were not well visualized on CT. In contrast, all of the lesions in LCH were seen as punched out (4/8), beveled-edge appearance (4/8) osteolytic masses in plain radiography, but scalp and dural extension could not be seen. Conclusion : Characteristic MR findings in patients with LCH are soft tissue mass in diploic space with extension to dura and scalp, and MRI would be better imaging modality than plain radiography or CT.
#Langerhans cell histiocytosis #Skull #Computed tomography #CT) #Magnetic resonance #MR)

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참고문헌 (28)

참고문헌 신청
/ 1996 / A multicentre retrospective survey of Langerhans’ cell histiocytosis: 348 cases observed between 1983 and 1993: The French Langerhans’ Cell Histiocytosis Study Gro google schola Al-Abbadi M / 1997 / Soft tissue Langerhans’ cell histiocytosis in an adult / Arch Pathol Lab Med 121 : 169 ~ 172 google schola Arceci RJ / 1999 / The histiocytoses: the fall of the Tower of Babel / Eur J Cancer 35 : 747 ~ 767 google schola Azouz EM / 2005 / Langerhans’cell histiocytosis: pathology, imaging and treatment of skeletal involvement / Pediatr Radiol 35 (2) : 103 ~ 15 google schola Broadbent V / 1989 / Histiocytosis syndromes in children. II. Approach to the clinical and laboratory evaluation of children with Langerhans cell histiocytosis / Med Pediatr google schola

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