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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한자기공명의과학회 Investigative Magnetic Resonance Imaging Investigative Magnetic Resonance Imaging 제22권 제2호
- 발행연도
- 2018.1
- 수록면
- 86 - 93 (8page)
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초록· 키워드
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Purpose: Imaging plays a significant role in diagnosing leptomeningeal metastases. However, the most appropriate sequence for the detection of leptomeningeal metastases has yet to be determined. This study compares the efficacies of contrastenhanced T2 fluid attenuated inversion recovery (FLAIR) and contrast-enhanced 3D T1 black-blood fast spin echo (FSE) imaging for the detection of leptomeningeal metastases. Materials and Methods: Tube phantoms containing varying concentrations of gadobutrol solution were scanned using T2 FLAIR and 3D T1 black-blood FSE. Additionally, 30 patients with leptomeningeal metastases were retrospectively evaluated to compare conspicuous lesions and the extent of leptomeningeal metastases detected by T2 FLAIR and 3D T1 black-blood FSE. Results: The signal intensities of low-concentration gadobutrol solutions (< 0.5 mmol/L) on T2 FLAIR images were higher than in 3D T1 black-blood FSE. The T2 FLAIR sequences exhibited significantly greater visual conspicuity scores than the 3D T1 black-blood sequence in leptomeningeal metastases of the pial membrane of cistern (P = 0.014). T2 FLAIR images exhibited a greater or equal extent (96.7%) of leptomeningeal metastases than 3D T1 black-blood FSE images. Conclusion: Because of its high sensitivity even at low gadolinium concentrations, contrast-enhanced T2 FLAIR images delineated leptomeningeal metastases in a wider territory than 3D T1 black-blood FSE.
목차
등록된 정보가 없습니다.
참고문헌 (32)
참고문헌 신청
Grossman SA / 1999 / Leptomeningeal carcinomatosis / Cancer Treat Rev 25:103~119
Wasserstrom WR / 1982 / Diagnosis and treatment of leptomeningeal metastases from solid tumors: experience with 90 patients / Cancer 49:759~772
Kremer S / 2006 / Accuracy of delayed post-contrast FLAIR MR imaging for the diagnosis of leptomeningeal infectious or tumoral diseases / J Neuroradiol 33:285~291
Misaki K / 2001 / Contrast-enhanced fluid-attenuated inversion recovery MRI is useful to detect the CSF dissemination of glioblastoma / J Comput Assist Tomogr 25:953~956
Mathews VP / 1999 / Brain: gadolinium-enhanced fast fluid-attenuated inversion-recovery MR imaging / Radiology 211:257~263
Wasserstrom WR / 1982 / Diagnosis and treatment of leptomeningeal metastases from solid tumors: experience with 90 patients / Cancer 49:759~772
Kremer S / 2006 / Accuracy of delayed post-contrast FLAIR MR imaging for the diagnosis of leptomeningeal infectious or tumoral diseases / J Neuroradiol 33:285~291
Misaki K / 2001 / Contrast-enhanced fluid-attenuated inversion recovery MRI is useful to detect the CSF dissemination of glioblastoma / J Comput Assist Tomogr 25:953~956
Mathews VP / 1999 / Brain: gadolinium-enhanced fast fluid-attenuated inversion-recovery MR imaging / Radiology 211:257~263
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