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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한자기공명의과학회 Investigative Magnetic Resonance Imaging Investigative Magnetic Resonance Imaging 제19권 제2호
- 발행연도
- 2015.1
- 수록면
- 67 - 75 (9page)
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Purpose: To investigate the value of image post-processing software (FreeSurfer,IBASPM [individual brain atlases using statistical parametric mapping software])and inversion time (TI) in volumetric analyses of the hippocampus and to identifydifferences in comparison with manual tracing.
Materials and Methods: Brain images from 12 normal adults were acquired usingmagnetization prepared rapid acquisition gradient echo (MPRAGE) with a slicethickness of 1.3 mm and TI of 800, 900, 1000, and 1100 ms. Hippocampal volumeswere measured using FreeSurfer, IBASPM and manual tracing. Statistical differenceswere examined using correlation analyses accounting for spatial interpretationspercent volume overlap and percent volume difference.
Results: FreeSurfer revealed a maximum percent volume overlap and maximumpercent volume difference at TI = 800 ms (77.1 ± 2.9%) and TI = 1100 ms (13.1 ±2.1%), respectively. The respective values for IBASPM were TI = 1100 ms (55.3 ±9.1%) and TI = 800 ms (43.1 ± 10.7%). FreeSurfer presented a higher correlation thanIBASPM but it was not statistically significant.
Conclusion: FreeSurfer performed better in volumetric determination than IBASPM.
Given the subjective nature of manual tracing, automated image acquisition andanalysis image is accurate and preferable.
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참고문헌 (25)
참고문헌 신청
Aleman-Gomez Y / 2006 / IBASPM: toolbox for automatic parcellation of brain structures. Presented at the 12th Annual Meeting of the organization for human brain mapping, Jun
Brewer JB / 2009 / Fully-automated volumetric MRI with normative ranges: translation to clinical practice / Behav Neurol 21 : 21 ~ 28
Chupin M / 2008 / Fully automatic hippocampus segmentation discriminates between early alzheimer's disease and normal aging / Biomedical imaging from nano to macro: 5th IEEE Intern
Dickerson BC / 2001 / MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease / Neurobiol Aging 22 : 747 ~ 754
Fischl B / 2012 / FreeSurfer / Neuroimage 62 : 774 ~ 781
Brewer JB / 2009 / Fully-automated volumetric MRI with normative ranges: translation to clinical practice / Behav Neurol 21 : 21 ~ 28
Chupin M / 2008 / Fully automatic hippocampus segmentation discriminates between early alzheimer's disease and normal aging / Biomedical imaging from nano to macro: 5th IEEE Intern
Dickerson BC / 2001 / MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease / Neurobiol Aging 22 : 747 ~ 754
Fischl B / 2012 / FreeSurfer / Neuroimage 62 : 774 ~ 781
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