하인두 편평상피암종의 경부 림프절 전이의 유형 및 의의

주영훈; 선동일; 조정해; 박준욱; 이성훈; 최봉진; 김준엽; 김민식

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자료유형: 학술저널

저자정보: 주영훈 선동일 조정해 박준욱 이성훈 최봉진 김준엽 김민식

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제52권 제9호

발행연도: 2009.1

수록면: 756 - 761 (6page)

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이 논문의 연구 히스토리 (3)

2009

하인두 편평세포암종의 경부 림프절 전이의 유형 및 의의

주영훈 , 선동일 , 조정해 외 5명 대한두경부종양학회 학술대회 2009.01 학술대회자료

하인두 편평상피암종의 경부 림프절 전이의 유형 및 의의

주영훈 , 선동일 , 조정해 외 5명 대한이비인후-두경부외과학회지 2009.01 학술저널

조기 구강설 편평상피암종에서 경부 림프절 전이 인자 분석

주영훈 , 선동일 , 조정해 외 3명 대한이비인후-두경부외과학회지 2009.01 학술저널

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Background and Objectives The aim of this study was to evaluate the incidence and prognostic significance of cervical lymph node metastasis in squamous cell carcinoma (SCC) of the hypopharynx. Subjects and Method A retrospective review of the 64 patients who were previously untreated for SCC of the hypopharynx and underwent surgery was performed from October 1993 to June 2008. Fifty-six patients had simultaneous bilateral neck dissection, whereas eight had unilateral neck dissection. Results The median age was 61.0 years (range, 34-75 years) for the study group consisting of 62 males and two females. Evaluating according to the N stages, there were 15 (23.4%), 10 (15.6%), 37 (57.8%), and 2 (3.1%) cases with N0, N1, N2 and N3, respectively. Forty-nine patients (76.6%) had pathologically proven cervical metastasis. Contralateral occult lymph node metastasis occurred in 20.5%. Ipsilateral and contralateral occult metastasis rates for clinically node negative patients were 41.2% and 11.8%, respectively. The most frequent sites for positive neck nodes occuring at each level were as follows: II (48.5%), level III (40.6%), level IV (26.6%), paratracheal node (21.4%), level V (9.4%), levels I (7.8%), and retropharyngeal node (6.3%). The 5-year overall survival and disease-specific survival rates were 50% and 53%, respectively. Cervical nodal metastasis (p=0.044) was statistically significant prognostic factors for disease-specific survival. Conclusion Metastasis to the cervical lymph node group is very frequent and has an impact on survival in patients with hypopharyngeal SCC. Therefore, we advocate bilateral neck dissection in patients with hypopharyngeal SCC with clinically positive metastasis. Ipsilateral elective neck dissection may be needed for clinically node negative patients.

#Hypopharynx·Squamous cell carcinoma·Lymphatic metastasis·Neck dissection

참고문헌 (19)

참고문헌 신청

Amatsu M / 2001 / Significance of retropharyngeal node dissection at radical surgery for carcinoma of the hypopharynx and cervical esophagus / Laryngoscope 111 (6) : 1099 ~

Bataini JP / 1985 / Natural history of neck disease in patients with squamous cell carcinoma of oropharynx and pharyngolarynx / Radiother Oncol 3 (3) : 245 ~ 255

Buckley JG / 2000 / Cervical node metastases in laryngeal and hypopharyngeal cancer: a prospective analysis of prevalence and distribution / Head Neck 22 (4) : 380 ~ 385

Candela FC / 1990 / Patterns of cervical node metastases from squamous carcinoma of the oropharynx and hypopharynx / Head Neck 12 (3) : 197 ~ 203

Chu PY / 2008 / Clinical and pathologic predictors of survival in patients with squamous cell carcinoma of the hypopharynx after surgical treatment / Ann Otol Rhinol Laryngo

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