조기 구강설 편평세포암종의 잠재적 경부림프절 전이

임영창; 안재윤; 구본석; 천제영; 김유석; 박영민; 최은창; 이진석

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자료유형: 학술저널

저자정보: 임영창 안재윤 구본석 천제영 김유석 박영민 최은창 이진석

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제49권 제4호

발행연도: 2006.1

수록면: 407 - 410 (4page)

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Background and Objectives：The most significant prognosticator of survival for patients with squamous cell carcinoma of the oral tongue has been the association of neck nodal metastasis. However, no consensus exists as to whether an elective neck dissection should be performed in patients with early oral tongue squmous cell carcinoma with a clinically negative neck.Subjects and Method：A retrospective analysis was performed on 54 early oral tongue squamous cell carcinoma patients (T1=26 and T2=28) with clinically negative necks who were treated between 1992 to 2003. All patients had an ipsilateral neck dissection and 29 patients had a contralateral neck dissection. Surgical treatment was followed by postoperative radiotherapy in 20 patients. The follow-up period ranged from 3 to 110 months (mean, 56 months). Data were analyzed using the Kaplan-Meier method, log-rank test, and the chi-square test. Results：Clinically occult, but pathologically positive ipsilateral lymph nodes were found in 26% (14/54) and contralateral lymph nodes in 3% (1/29). Based on the clinical staging of the tumor, 19% (5 of 26) of the cases showed lymph node metastases in T1 tumors, and 36% (10 of 28) in T2. All regional recurrences developed in the ipsilateral necks, there was no cases of contralateral neck recurrence. Patients with no evidence of occult nodal cancer have significantly improved disease-specific free survival rates over patients with any pathologically positive nodes (5 year disease specific survival rate, 90% vs 38%, p0.05). Conclusion：This study showed that ipsilateral elective neck dissection should be performed for early oral tongue cancers. On the other hand, our series suggests that it may not be harmful to observe the contralateral N0 neck in the treatment of early oral tongue cancer. (Korean J Otolaryngol 2006;49:407-10)

#설암·림프절 전이·경부청소술. #Tongue neoplasm·Lymphatic metastasis·Neck dissection.

참고문헌 (20)

참고문헌 신청

/ / Experience of the Curie Institute in treatmentof cancer of the mobile tongue Management of the necknodes : 503 ~ 8

/ 1972 / Nodal metastases and prognosis in carcinoma of the oralcavity 5 : 333 ~ 42

/ 1976 / Neck dissection in the treatmentof carcinoma of the anterior two-thirds of the tongue 143 : 75 ~ 80

/ 1977 / Surgical treatment of squamouscell carcinoma of the oral tongue:Factors influencing survival 103 : 212 ~ 5

/ 1980 / Management of T1 carcinomaof the anterior aspect of the tongue 106 : 249 ~ 51

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