1.5 cm 이하 크기의 갑상선 유두상암종의 임상적 양상

유익원; 정은재; 백승국; 정광윤; 김신곤

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자료유형: 학술저널

저자정보: 유익원 정은재 백승국 정광윤 김신곤

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제52권 제7호

발행연도: 2009.1

수록면: 599 - 603 (5page)

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Background and Objectives With the increasing use of high resolution sonography and fine needle aspiration biopsy, the proportion of newly diagnosed thyroid papillary carcinomas have increased. However, it is not entirely clear whether microcarcinomas detectable by the above technology the should be considered a threshold for risk evaluation. The purpose of this study is to evaluate the clinical behavior of papillary carcinomas smaller than 1.5 cm. Subjects and Method A retrospective chart review was conducted for 181 patients who underwent surgery for thyroid cancer and was proven to have papillary carcinoma smaller than 1.5 cm in size from 1997 to 2006. The patients were divided into 3 groups according to cancer size. The patient’s gender, age, surgical method, pathology, initial neck node and neck recurrence was analyzed by chi-square test, analysis of variance (ANOVA) test and multinomial logistic regression analysis. Results Progressively increasing frequency of signs of tumor aggressiveness (multifocal, bilateral, extracapsular spread) was observed with increasing size. The rate of lymph node metastasis increased also, but it did not reach a significant value. Despite the increasing rate of aggressiveness and lymph node metastasis, there was no significant difference in recurrence between these groups. Conclusion Although the long term outcome does not seem to directly depend on tumor size in these small thyroid cancers, a progressing frequency of aggressiveness with increasing cancer size at presentation is evident.

#Thyroid gland·Papillary·Carcinoma

참고문헌 (14)

참고문헌 신청

Appetecchia M / 2002 / Outcome after treatment of papillary thyroid microcarcinoma / J Exp Clin Cancer Res 21 (2) : 159 ~ 164

Bramley MD / 1996 / Papillary microcarcinoma of the thyroid gland / Br J Surg 83 (12) : 1674 ~ 1683

Chow SM / 2003 / Papillary microcarcinoma of the thyroid-Prognostic significance of lymph node metastasis and multifocality / Cancer 98 (1) : 3 ~ 40

Gross ND / 2001 / MRI detection of cervical metastasis from differentiated thyroid carcinoma / Larygoscope 111 (11) : 1905 ~ 1909

Harach HR / / A systemic autopsy study / 1985 56 (3) : 531 ~ 538

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