Efficacy and Safety of Guardcel Nasal Packing After Endoscopic Sinus Surgery: A Prospective, Single-Blind, Randomized Controlled Study

강병진; 김정록; 신재민; 박일호; 이흥만

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자료유형: 학술저널

저자정보: 강병진 김정록 신재민 박일호 이흥만

저널정보: 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제10권 제3호

발행연도: 2017.1

수록면: 248 - 253 (6page)

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Objectives. Nasal packing after endoscopic sinus surgery is frequently used to control postoperative bleeding, enhance the wound healing process, and prevent lateralization of the middle turbinate, which causes insufficient ventilation. Many biodegradable materials have been developed to reduce pain and mucosal damage during packing removal. The purpose of this study was to compare the efficacy of Guardcel (Genewel Co.) middle meatal packing with a traditional nonabsorbable middle meatal packing, Merocel (Medtronic Xomed), on wound healing and patient satisfaction. Methods. In this prospective, single-blind, randomized controlled study, we enrolled 32 consecutive patients (64 nostrils) undergoing bilateral endoscopic sinus surgery at Korea University Guro Hospital from February 2015 to August 2015. Guardcel and Merocel were inserted postoperatively into a randomly assigned side. Objective findings about bleeding, hemostasis, adhesion, and infection were evaluated with nasal endoscopy. Patients’ symptoms including pain and nasal obstruction were evaluated with a visual analog scale. Each evaluation was done at 2–3 days, 1 week, 2 weeks, and 4 weeks after surgery. Results. At 2–3 days after endoscopic sinus surgery, the Guardcel side had a significantly less hemostasis time than the Merocel side (P=0.001). During this period, the pain during packing removal was significantly lower on the Guardcel-inserted side than the Merocel-inserted side (P=0.002). At two weeks after surgery, the adhesion score on the Guardcel side was significantly lower than that of the Merocel side (P=0.011). Other parameters during the study follow-up periods were not statistically significant. There were no severe adverse reactions. Conclusion. Guardcel, a newly developed packing material, appeared to shorten the hemostasis time and reduce pain sensation at 2–3 days after surgery; it also prevented adhesion formation 2 weeks after surgery when compared with the control. Guardcel can be an effective and safe candidate to replace conventional packing materials after endoscopic sinus surgery.

#Nasal Packing #Absorbable Packing #Hemostasis #Adhesion #Endoscopic Sinus Surgery

참고문헌 (11)

참고문헌 신청

Benninger MS / 2003 / Adult chronic rhinosinusitis: definitions, diagnosis, epidemiology, and pathophysiology / Otolaryngol Head Neck Surg 129 (3 Suppl) : S1 ~ S32

Berlucchi M / 2009 / Endoscopic outcomes of resorbable nasal packing after functional endoscopic sinus surgery: a multicenter prospective randomized controlled study / Eur Ar

Govindaraj S / 2010 / Endoscopic sinus surgery: evolution and technical innovations / J Laryngol Otol 124 (3) : 242 ~ 250

Kastl KG / 2009 / Effect of carboxymethylcellulose nasal packing on wound healing after functional endoscopic sinus surgery / Am J Rhinol Allergy 23 (1) : 80 ~ 84

Kim YS / 2011 / Prevalence and risk factors of chronic rhinosinusitis in Korea / Am J Rhinol Allergy 25 (3) : 117 ~ 121

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