두경부 혈관부종에 대한 임상적 고찰

이준규; 최현석; 윤태미; 김각; 서덕중; 임상철

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자료유형: 학술저널

저자정보: 이준규 최현석 윤태미 김각 서덕중 임상철

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제51권 제8호

발행연도: 2008.1

수록면: 726 - 730 (5page)

이용수

📌

연구주제

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연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

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Angioedema is a localized, nonpitting edema resulting from extravasation of fluid into the interstitial space. It usually develops suddenly and fades during the course of 24 to 48 hours. However, angioedema of the upper respiratory tract can result in serious acute respiratory distress, airway obstruction, and death. The purpose of this study was to analyze clinical characteristics of angioedema in the head and neck. Subjects and Method：A review of 144 patients with angioedema of the head and neck over 3-year period was conducted. Results：The presumptive causes were 115 allergic reactions to food, drug, or environmental exposure, 3 losses of C1 esterase inhibitor, 1 angiotensin-converting enzyme inhibitor use, and 25 idiopathic conditions. The main locations of the edema were 100 face/lips, 4 oral cavity/oropharynx, 5 larynx/hypopharynx, and 35 multiple sites of the head and neck. Most of patients were treated with steroids and H1 and H2 blockers. All of 7 patients with low oxygen saturation and 14 out of 18 patients with hypotension on arrival were improved within 24 hours. There were 4 patients with airway distress treated with urgent airway intervention, three of them were completely recovered within 110-240 hours but one of them died of the disease. Patients with the cause of idiopathic and loss of C1 esterase inhibitor were found to stay longer in the hospital over 48 hours (p<0.05). Conclusion：Angioedema of the head and neck usually responds well to the treatment. However, there might be cases with life-threatening airway obstruction. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:726-30)

#Angioedema·Head and neck.

참고문헌 (16)

참고문헌 신청

Agah R / 1997 / Angioedema: The role of ACE inhibitors and factors associated with poor clinical outcome / Intensive Care Med 23 (7) : 793 ~ 796

Barna JS / 1990 / Life-threatening angioedema / Otolaryngol Head Neck Surg 103 (5) : 795 ~ 798

Goldberg R / 1993 / Evaluation and management of acute uvular edema / Ann Emerg Med 22 (2) : 251 ~ 255

Gunkel AR / 1996 / Angioneurotic edema as a reaction to angiotensin-converting enzyme inhibitors / Am J Otolaryngol 17 (2) : 87 ~ 91

Ishoo E / 1999 / Predicting airway risk in angioedema: Staging system based on presentation / Otolaryngol Head Neck Surg 121 (3) : 263 ~ 268

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