지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.1
- 수록면
- 677 - 683 (7page)
이용수
초록· 키워드
오류제보하기
Background and Objectives：Our previous study showed that nonsteroidal anti-inflamatory drug-activated gene (NAG-1) induced apoptosis in tongue cancer cels. However, the NAG-1 expression in tongue cancer and normal tisues was not studied. The aim of this study was to investigate the expression of NAG-1 in oral tongue cancer and normal tissues and to identify the as a valuable prognostic marker in tongue cancer. Subjects and Method：The medical records and pathologic reports of 42 tongue cancer patients who received surgery as primary treatment were surveyed. Tongue cancer and normal tissues, which were obtained during the operation, were stained with anti-NAG-1 antibody using the immunohistochemical method and the H-score was calculated. Results：As a result, the higher expression of NAG-1 was observed in the cancer tissues than in the normal tissues. por prognosis. A 5-year survival rate was significantly decreased in cases showing higher NAG-1 expresion in the cancer tissues than in the normal tisues. Conclusion：The higher NAG-1 expression in the cancer tissue suggests malignant changes in cancer tisue and poor prognosis. Therefore, NAG-1 may be a useful prognostic marker in tongue squamous cel carcinoma. (Korean J Otorhinolaryngol-Head Neck Surg 2007 ;50 :677-83)
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
/ 1997 / Human cDNA encoding a novel TGF-β superfamily protein highly expressed in placenta 122 (3) : 622 ~ 626
/ 1997 / Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta 203 (1) : 17 ~ 26
/ 1998 / Cloning and characterization of a novel member of the transforming growth factor-β/bone morphogenetic protein family 273 (22) : 13760 ~ 13767
/ 1999 / DPC4/SMAD4 mediated tumor suppressionof colon carcinoma cells is associated with reduced urokinase expression 18 (20) : 3152 ~ 3158
/ 2001 / Cyclooxygenase regulate the expression of a TGF-β superfamily member that has proapoptotic and antitumorigenic activities 59 (4) : 901 ~ 908
/ 1997 / Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta 203 (1) : 17 ~ 26
/ 1998 / Cloning and characterization of a novel member of the transforming growth factor-β/bone morphogenetic protein family 273 (22) : 13760 ~ 13767
/ 1999 / DPC4/SMAD4 mediated tumor suppressionof colon carcinoma cells is associated with reduced urokinase expression 18 (20) : 3152 ~ 3158
/ 2001 / Cyclooxygenase regulate the expression of a TGF-β superfamily member that has proapoptotic and antitumorigenic activities 59 (4) : 901 ~ 908
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
간암 세포주 및 위암 세포주에서 Nonsteroidal Anti-inflammatory Drug Activated Gene (NAG-1)의 기능 연구
Journal of Pathology and Translational Medicine
2007 .01
-
사람 코점막과 배양된 코점막 상피세포에서 Nonsteroidal Anti-Inflammatory Drug-Activated Gene-1(NAG-1)의 발현
대한이비인후-두경부외과학회지
2003 .01
-
사람 구강암종 세포주에서 Non-Steroidal Anti-Inflammatory Drug-Activated Gene(NAG-1)의 유도 및 세포고사 작용
대한이비인후-두경부외과학회지
2004 .01
-
N-Acetyl-D-glucosamine (NAG)의 피부주름 개선 효과
대한화장품학회지
2004 .01
-
Characteristics of Oral Tongue and Base of the Tongue Cancer: A Hospital Cancer Registry Based Analysis
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
설진과 종양의 관계에 대한 연구
대한한방종양학회지
2003 .01
-
Urinary N-Acetyl-beta-D-Glucosaminidase and beta 2-Microglobulin in Children with Various Renal Diseases
Childhood Kidney Diseases
2008 .01
-
Dysphagia in Tongue Cancer Patients
Annals of Rehabilitation Medicine
2015 .01
-
Personalized Approach for Tongue Cancer
대한두경부종양학회 학술대회
2009 .01
-
Profile and Survival of Tongue Cancer Patients in "Dharmais" Cancer Hospital, Jakarta
Asian Pacific journal of cancer prevention : APJCP
2014 .01
-
Clinical Outcome of Squamous Cell Carcinoma of the Tongue in Young Patients: A Stage-Matched Comparative Analysis
Clinical and Experimental Otorhinolaryngology
2010 .01
-
음식물 섭취로 인한 혀 색상 변화가 설진에 미치는 영향
동의생리병리학회지
2020 .08
-
카드뮴을 투여한 흰쥐에서 신피질의 Malondialdehyde 농도와 요중 NAG 활성도간의 관계
항공우주의학회지
2001 .09
-
정상 설색의 수치적 기준에 관한 고찰
대한한의진단학회지
2013 .01
-
영아의 혀에 발생한 육아조직 1례
영남의대학술지
2005 .01
-
설기저부로 전이된 소세포 폐암종 1예
대한 두경부 종양 학술지
2005 .01
-
Relationships between Tumor Volume and Lymphatic Metastasis and Prognosis in Early Oral Tongue Cancer
Clinical and Experimental Otorhinolaryngology
2013 .01
-
p53 Expression Helps Identify High Risk Oral Tongue Premalignant Lesions and Correlates with Patterns of Invasive Tumour Front and Tumour Depth in Oral Tongue Squamous Cell Carcinoma Cases
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Ra Needle을 이용한 Tongue Cancer의 치료에 대한 고찰
대한방사선치료학회지
1990 .01
-
설진 기기의 시스템 구성 및 진단 방법 개발
한국한의학연구원 논문집
2008 .12
이 논문의 저자 정보
최근 본 자료
댓글(0)
0