Clinical Outcome of Squamous Cell Carcinoma of the  Tongue in Young Patients: A Stage-Matched  Comparative Analysis

박준욱; 선동일; 조광재; 조영훈; 유화종; 김민식

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자료유형: 학술저널

저자정보: 박준욱 선동일 조광재 조영훈 유화종 김민식

저널정보: 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제3권 제3호

발행연도: 2010.1

수록면: 161 - 165 (5page)

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Objectives. The reported incidence of tongue cancer in young patients has recently increased. The aim of this study was to analyze the clinical characteristics of tongue cancer in a young group of patients, and to compare them with those of an older group of tongue cancer patients. Methods. We retrospectively reviewed the records of 85 patients who were diagnosed with squamous cell carcinoma of the tongue. They were divided into two age groups: over 45 years of age and under 45 years. To compare the prognosis of similarly staged patients in the group, each age group was divided into the early (stage I, II) and advanced stage groups (stage III, IV), and then they were compared. The young group consisted of 23 patients and the older group had 62 patients. Results. At the early stage, the clinical prognosis of the patients in both age groups was good, and no significant difference was observed. However, at the advanced stage, the overall and regional recurrence rates were significantly higher in the younger age group as compared to that in the old age group (P=0.007, P=0.001, respectively). The diseasespecific survival rate of the patients in the young group was significantly lower than that in the old age group (P=0.025). Conclusion. Tongue cancer in young subjects has significantly different clinical outcomes according to the stage. The clinical outcome of the advanced-stage tongue cancer in young subjects was poorer than that in the older subjects. Regional recurrence seemed to be the main cause of the poor prognosis.

#Tongue #Squamous cell carcinoma #Young adult

참고문헌 (18)

참고문헌 신청

Amsterdam JT / 1982 / Squamous cell carcinoma of the oral cavity in young adults / J Surg Oncol 19 (2) : 65 ~ 68

Atula S / 1996 / Cancer of the tongue in patients younger than 40 years: a distinct entity? / Arch Otolaryngol Head Neck Surg 122 (12) : 1313 ~ 1319

Chitapanarux I / 2006 / Oral cavity cancers at a young age: analysis of patient, tumor and treatment characteristics in Chiang Mai University Hospital / Oral Oncol 42 (1) : 8

Clark RM / 1982 / Malignant tumors of the head and neck in a young population / Am J Surg 144 (4) : 459 ~ 462

Friedlander PL / 1998 / Squamous cell carcinoma of the tongue in young patients: a matched-pair analysis / Head Neck 20 (5) : 363 ~ 368

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박준욱

소속기관 Department of Otolaryngology-Head and Neck Surgery Eunpyeong St. Mary’s Hospital College of Medicine The Catholic University of Korea