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학술저널
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한국심초음파학회 Journal of Cardiovascular Imaging Journal of Cardiovascular Imaging 제26권 제3호
발행연도
2018.1
수록면
147 - 154 (8page)

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BACKGROUND: Sequential changes in left ventricular (LV) systolic function over time inpatients with recurrent episodes of Kawasaki disease (KD) remain unclear. METHODS: Twenty-five children with recurrent KD were retrospectively studied. Usingconventional echocardiographic parameters and myocardial deformation analysis, systolicLV function in children in initial and recurrent KD episodes were compared with separatecontrol groups, comprising 15 controls each. Recurrent KD was defined as occurring at aninterval of ≥2 months between the initial and recurrent episodes. RESULTS: The interval range between initial and recurrent episodes of KD was 3–103 months. In children with KD, 8 (32%) were <1 year of age at the initial episode, 10 (40%) had arecurrence within 1 year of the initial episode, and 4 (16%) and 5 (20%) were intravenousimmune globulin nonresponders in initial and recurrent episodes, respectively. In both theinitial and recurrent episodes of KD, the mean LV longitudinal peak systolic ε was all withinnormal range. However, when compared to controls, mean LV longitudinal peak systolicε was decreased in patients with KD in the acute phases of both the initial and recurrentepisodes. When compared to controls, mean LV longitudinal peak systolic ε was decreased inpatients with KD in the convalescent phase of the recurrent episodes. CONCLUSIONS: Subclinical decreases in myocardial systolic deformation, as evidenced bydecreased LV longitudinal peak systolic ε, may persist in children in the convalescent phaseof recurrent KD; further studies involving larger numbers of patients may be needed forverification.

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