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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 42 - 47 (6page)
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초록· 키워드
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Background: Previously, the authors revealed that epicardial fat thickness was significantly correlated with the severity of coronary artery disease in patients with known coronary artery disease. We evaluated whether echocardiographic epicardial fat thickness was associated with short term prognosis in patients with acute coronary syndrome.
Methods: Two hundred and sixty five consecutive acute coronary syndrome (ACS) patients who underwent successful coronary stenting were studied. Epicardial fat thickness on the free wall of right ventricle was measured at end-diastole from the parasternal long-axis views of three cardiac cycles. 30 days follow-up was obtained in all patients and clinical outcomes were compared with epicardial fat thickness.
Results: Mean value of epicardial fat thickness was 5.36 mm (range 0.44 to 16.55 mm). Major adverse cardiac events(MACE) were developed in 19 patients (7.2%) during 30 days; 2 cases of cardiac death, 11 of non fatal Q wave myocardial infarction (QMI), 4 of revascularization and 2 of ischemic stroke. Incidence of occlusion by thrombi (4.5% vs. 21.2%, p=0.016), Gensini’s score (44.52±31.06 vs. 61.00±30.68, p=0.027) and epicardial fat thickness (5.19±2.13 vs. 7.51± 3.87 mm, p=0.018) were significantly higher in patients with MACE than those without MACE. Significant correlations were demonstrated between epicardial fat thickness and age (r=0.193, p=0.002), fibrinogen (r=0.145, p=0.022) and LDLcholesterol (r=0.136, p=0.027). Multivariate analysis showed that epicardial fat thickness (OR 1.479, 95% CI 1.183- 1.848, p=0.001) was an independent predictor of 30 days MACE.
Conclusion: Epicardial fat thickness was significantly correlated with short term prognosis in patients with ACS.
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등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Abbara S / 2005 / Mapping epicardial fat with multidetector computed tomography to facilitate percutaneous transepicardial arrhythmia ablation / Eur J Radiol 57 : 417 ~ 422
Baker AR / 2006 / Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease / Cardiovasc Diabetol 5 : 1 ~
Boersma E / 2000 / Predictors of outcome in patients with acute coronary syndromes without persistent STsegment elevation. Results from an international trial of 9461 patien
DeFronzo RA / 1991 / Insulin resistance. a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease / Diab
Doll S / 2002 / Body mass index, abdominal adiposity and blood pressure: consistency of their association across developing and developed countries / Int J Obes Relat Metab D
Baker AR / 2006 / Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease / Cardiovasc Diabetol 5 : 1 ~
Boersma E / 2000 / Predictors of outcome in patients with acute coronary syndromes without persistent STsegment elevation. Results from an international trial of 9461 patien
DeFronzo RA / 1991 / Insulin resistance. a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease / Diab
Doll S / 2002 / Body mass index, abdominal adiposity and blood pressure: consistency of their association across developing and developed countries / Int J Obes Relat Metab D
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