지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 65 - 74 (10page)
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초록· 키워드
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BACKGROUND: Increased epicardial fat is known to be associated with the presenceand chronicity of atrial fibrillation (AF). Free fatty acids (FFAs) are major componentsof epicardial fat; however, their potential association with AF in ischemic stroke has notbeen investigated. We aimed to assess the performance of echocardiographic epicardial fatthickness (EFT) and plasma FFA level in identifying patients with ischemic stroke and AF. METHODS: We enrolled a total of 214 consecutive patients (mean age, 66.8 ± 12.3 years;39.7% women) diagnosed with acute ischemic stroke between March 2011 and June 2014. Thepatients were divided into two groups: ischemic stroke with AF (n = 35, 16.4%) and ischemicstroke without AF (n = 179, 83.6%). RESULTS: The ischemic stroke with AF group showed significantly higher serum FFA level(1379.7 ± 717.5 vs. 757.8 ± 520.5 uEq/L, p < 0.0001) and EFT (6.5 ± 1.2 vs. 5.3 ± 1.2 mm, p < 0.001)than the group without AF. Multivariable logistic regression analysis demonstrated that age(odds ratio [OR], 1.112), serum FFA level (OR, 1.002), and EFT (OR, 1.740) were independentlyassociated with the ischemic stroke group with AF. EFT and FFA significantly improved thegoodness-of-fit and discriminability of the simple regression model including age as a covariate(log likelihood difference, 21.35; p < 0.001; c-index difference, 17.9%; p < 0.001). CONCLUSIONS: High EFT and serum FFA level were associated with ischemic stroke inpatients with AF. Echocardiographic EFT and serum FFA level can play a significant role inidentifying ischemic stroke with AF.
목차
등록된 정보가 없습니다.
참고문헌 (39)
참고문헌 신청
김범준 / 2014 / Ischemic Stroke Subtype Classification: An Asian Viewpoint / 대한뇌졸중학회지 16(1):8~17
Sanak D / 2015 / Paroxysmal atrial fibrillation in young cryptogenic ischemic stroke: A 3-week ECG Holter monitoring study / Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 159:283~287
Mozaffarian D / 2015 / Heart disease and stroke statistics--2015 update: a report from the American Heart Association / Circulation 131:e29~e322
Tsang TS / 2003 / The prevalence of atrial fibrillation in incident stroke cases and matched population controls in Rochester, Minnesota: changes over three decades / J Am Coll Cardiol 42:93~100
Grau AJ / 2001 / Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German stroke data bank / Stroke 32:2559~2566
Sanak D / 2015 / Paroxysmal atrial fibrillation in young cryptogenic ischemic stroke: A 3-week ECG Holter monitoring study / Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 159:283~287
Mozaffarian D / 2015 / Heart disease and stroke statistics--2015 update: a report from the American Heart Association / Circulation 131:e29~e322
Tsang TS / 2003 / The prevalence of atrial fibrillation in incident stroke cases and matched population controls in Rochester, Minnesota: changes over three decades / J Am Coll Cardiol 42:93~100
Grau AJ / 2001 / Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German stroke data bank / Stroke 32:2559~2566
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