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학술저널
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한국심초음파학회 Journal of Cardiovascular Imaging Journal of Cardiovascular Imaging 제24권 제1호
발행연도
2016.1
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40 - 47 (8page)

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Background: In adults, tissue Doppler imaging (TDI) is a recommended component of routine echocardiography. However,TDI velocities are less accepted in pediatrics, due to their strong variability and age dependence in children. This study examines thedistribution of myocardial tissue Doppler velocities in healthy children to assess the effect of age with cardiac growth on the variousechocardiographic measurements. Methods: Total 144 healthy children were enrolled in this study. They were recruited from the pediatric outpatient clinic for routinewell-child visits. The statistical relationships between age and TDI values were analyzed. Also, the statistical relationshipsbetween body surface area (BSA) and TDI values, left ventricle end-diastolic dimension (LVEDD) and TDI values were analyzed. Also, we conducted multivariate analysis of cardiac growth parameters such as, age, BSA, LVEDD and TDI velocity data. Results: All of the age, BSA, and LVEDD had positive correlations with deceleration time (DT), pressure half-time (PHT),peak early diastolic myocardial velocity, peak systolic myocardial velocity, and had negative correlations with peak late diastolic velocity(A) and the ratio of trans-mitral inflow velocity to early diastolic velocity of mitral annulus (E/E’). In the multivariate analysis,all of the age, BSA, and LVEDD had positive correlations with DT, PHT, and negative correlations with A and E/E’. Conclusion: The cardiac growth parameters related alterations of E/E’ may suggest that diastolic myocardial velocities are cardiacgrowth dependent, and diastolic function has positive correlation with cardiac growth in pediatric group. This cardiac growthrelated myocardial functional variation would be important for assessment of cardiac involvement either in healthy and sick child.

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