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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 592 - 604 (13page)
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초록· 키워드
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Objectives: This study is to review the effect of Korean medicinal herbs on treatment of benign prostatic hyperplasia induced in rat models, as reported in domestic and foreign journals. Methods: Six electronic databases (EMBASE, PubMed, Oasis, RISS, CENTRAL, and Koreankt) were searched with terms including benign prostatic hyperplasia to identify study reports on treatment of benign prostatic hyperplasia impairment with Korean medicinal herbs. After selecting several studies, the analysis focused on items reflected in the diagnosis of benign prostatic hyperplasia, such as prostate weight, thickness of the prostate epithelium, and prostate specific antigen. Results: Six studies were reviewed. Testosterone propionate was used as a benign prostatic hyperplasia induction material in all the included studies. Cinnamomum verum (CV), Cynanchum wilfordii (CW), Ponciri fructus (PF), Quisqualis indica (QI), Acorus gramineus (AG), and Melandrium firmum (MF) had reduced prostate weight statistically significantly. The QI gave a better response than finasteride in terms of reducing epithelium thickness, and the response was statistically significant. The prostate specific antigen level was lower in the group treated with CV than in the control group. Conclusions: CV, CW, PF, QI, AG, and MF had distinct therapeutic effects. However it is difficult to determine which of these is better by comparing them numerically because the observation items evaluated in a rat model of benign prostatic hyperplasia.
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참고문헌 (49)
참고문헌 신청
Nickel JC / 2008 / Inflammation and Benign Prostatic Hyperplasia / Urol Clin North Am 35(1):109~115
Edwards JL / 2008 / Diagnosis and management of benign prostatic hyperplasia / Am Fam Physician 77(10):1403~1410
McConnell JD / 1991 / The pathophysiology of benign prostatic hyperplasia / J Androl 12(6):356~363
Thigpen AE / 1993 / Tissue distribution and ontogeny of steroid 5alpha-reductase isozyme expression / J Clin Invest 92(2):903~910
Steers WD / 2001 / 5alpha-reductase activity in the prostate / Urology 58(6):17~24
Edwards JL / 2008 / Diagnosis and management of benign prostatic hyperplasia / Am Fam Physician 77(10):1403~1410
McConnell JD / 1991 / The pathophysiology of benign prostatic hyperplasia / J Androl 12(6):356~363
Thigpen AE / 1993 / Tissue distribution and ontogeny of steroid 5alpha-reductase isozyme expression / J Clin Invest 92(2):903~910
Steers WD / 2001 / 5alpha-reductase activity in the prostate / Urology 58(6):17~24
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