지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 113 - 117 (5page)
이용수
초록· 키워드
오류제보하기
Objectives : in recent years, there have been some case reports about liver injuries suspected to be caused by Heshouwu, the root of Polygonum multiflorum. So, I investigated liver function tests of patients who had taken Heshouwu, to know whether Heshouwu was hepatotoxic.
Methods : I surveyed whether Heshouwu caused liver injury in patients, who had been admitted and taken Heshouwu at Dongguk University International Hospital, from May 2005 to July 2008. I looked over all the liver function tests of those patients, done during medication and 30 days after.
Results : Among 1,449 inpatients, there were 124 patients who had taken Heshouwu. Among those 124 patients, 14 cases whose liver function tests were abnormal before medication were excluded. 69 cases who did not take liver function test 30 days after were also excluded. As a result, 41 patients were enrolled, and their mean dosage was 14.04(8-24) g/day, and the mean medication period was 13.8 (1-89) days. During and after medication, there were no abnormal liver function test results at all, in the enrolled cases.
Conclusions : Roughly speaking, according to the above results, it seems that taking Heshouwu for about two weeks as per the commonly taken dosage did not cause hepatotoxicity, though we needs more laboratory and clinical research to reach a more definitive conclusion.
목차
등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
Benichou C / 1990 / Criteria of drug-induced liver disorders. Report of an international consensus meeting / J Hepatol 11 (2) : 272 ~ 276
But PP / 1996 / Hepatitis related to the Chinese medicine Shou-wu-pian manufactured from Polygonum multiflorum / Vet Hum Toxicol 38 (4) : 280 ~ 282
Cardenas A / 2006 / Acute hepatitis due to shen-min: a herbal product derived from Polygonum multiflorum / J Clin Gastroenterol. 40 (7) : 629 ~ 632
Maria VA / 1997 / Development and validation of a clinical scale for the diagnosis of drug-induced hepatitis / Hepatology 26 (3) : 664 ~ 669
Mazzanti G / 2004 / New case of acute hepatitis following the consumption of Shou Wu Pian, a Chinese herbal product derived from Polygonum multiflorum / Ann Intern Med 140 (
But PP / 1996 / Hepatitis related to the Chinese medicine Shou-wu-pian manufactured from Polygonum multiflorum / Vet Hum Toxicol 38 (4) : 280 ~ 282
Cardenas A / 2006 / Acute hepatitis due to shen-min: a herbal product derived from Polygonum multiflorum / J Clin Gastroenterol. 40 (7) : 629 ~ 632
Maria VA / 1997 / Development and validation of a clinical scale for the diagnosis of drug-induced hepatitis / Hepatology 26 (3) : 664 ~ 669
Mazzanti G / 2004 / New case of acute hepatitis following the consumption of Shou Wu Pian, a Chinese herbal product derived from Polygonum multiflorum / Ann Intern Med 140 (
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