지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치주과학회 Journal of Periodontal & Implant Science Journal of Periodontal & Implant Science 제39권 제2호
- 발행연도
- 2009.1
- 수록면
- 167 - 176 (10page)
이용수
초록· 키워드
오류제보하기
Purpose: The purpose of this study is to histologically and histomorphometrically evaluate the effect of PLGA on bone
regeneration compared with bone graft material.
Methods: The experimental study was conducted in 10 rabbits with 2 different healing periods of 2 and 4 weeks. Following
surgical exposure of the calvarium, 4 circular bone defects with a diameter of 4.6mm were formed. Rabbits were divided into
control group, test groups I, and II. 10 defects assigned to the test group Ⅰ were grafted with Nu-oss and other 10 defects
assigned to the test group II were grafted with PLGA. The rest of the defects were in the negative control group. At 2nd and
4th week after surgery, 10 rabbits were sacrificed through intracardiac perfusion and then specimens were obtained. Histological
analysis was performed following staining with trichorme and transversal sectioning of the calvarial bone.
Results: A group which used PLGA showed tissue reactions characterized by severe inflammation, rather than distinctive new
bone formation.
Conclusions: The present experimental investigations have failed to prove any beneficial effects of PLGA. PLGA used in this
study exhibited foreign body reactions and a less favorable pattern of new bone formation in comparison to control group.
Conclusion: PLGA did not function as scaffold. Further investigations of many types of micro PLGA that could improve its
potential in GBR procedures are needed. (J Korean Acad Periodontol 2009;39:167-176)
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Athreya SA / 1999 / Impedance spectroscopy of protein polymer modified silicon micromachined probes / Sensors Actuators 72 : 203 ~ 216
Becker W / 1988 / New attachment after treatment with root isolation procedures; report for treated class III and class II furcations and vertical osseous defects / Int J Pe
Bhattarai SR / 2004 / Novel biodegradable electrospun membrane: scaffold for tissue engineering / Biomaterials 25 : 2595 ~ 2602
Cai K / 2002 / Influence of different surface modification treatments on poly(d,l-lactic acid) with silk fibroin and their effects on the culture of osteoblast in vitro / Bi
Cai K / 2002 / Poly(d,l-lactic acid) surfaces modified by silk fibroin: effects on the culture of osteoblast in vitro / Biomaterials 23 : 1153 ~ 1160
Becker W / 1988 / New attachment after treatment with root isolation procedures; report for treated class III and class II furcations and vertical osseous defects / Int J Pe
Bhattarai SR / 2004 / Novel biodegradable electrospun membrane: scaffold for tissue engineering / Biomaterials 25 : 2595 ~ 2602
Cai K / 2002 / Influence of different surface modification treatments on poly(d,l-lactic acid) with silk fibroin and their effects on the culture of osteoblast in vitro / Bi
Cai K / 2002 / Poly(d,l-lactic acid) surfaces modified by silk fibroin: effects on the culture of osteoblast in vitro / Biomaterials 23 : 1153 ~ 1160
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Rabbit calvaria를 이용하여 hyaluronic acid (HA)를 처리한 poly (D,L-lactic-co-glycolic acid) 차폐막들의 골 생성능력에 대한 비교 연구
대한치과보철학회지
2010 .01
-
A Comparative study for single-shot immunization of diphtheria toxoid with combined PLGA microspheres.
대한약학회 학술대회
2002 .01
-
Biological Safety Evaluation of Synthetic Polymer
한국실험동물학회 학술발표대회 논문집
2003 .06
-
A study of bone regeneration effect according to the two different graft bone materials in the cranial defects of rabbits
Oral Biology Research
2018 .01
-
Bone defect model in animals for evaluation of bone grafts
한국실험동물학회 학술발표대회 논문집
2016 .02
-
PLGA-Based Nanoparticles as Cancer Drug Delivery Systems
Asian Pacific journal of cancer prevention : APJCP
2014 .01
-
Evaluation of bone formation after grafting with cancellous and cortical bone allografts in the treatment of bone defects around implants
Oral Biology Research
2011 .01
-
토끼 두개골 결손부에서 블록형과 분말형 hydroxyapatite의 골전도 효과
Journal of Periodontal & Implant Science
2009 .01
-
Comparison of the bone healing capacity of autogenous bone, demineralized freeze dried bone allograft, and collagen sponge in repairing rabbit cranial defects
대한구강악안면외과학회지
2012 .01
-
구개부에 발생한 다형성 저등급 선암종의 치험례
대한구강악안면외과학회지
2011 .01
-
PLGA 종류와 담체의 형성 방법에 따른 인간의 조직공학적 연골형성
의공학회지
2002 .01
-
Lamination of microfibrous PLGA fabric by electrospinning a layer of collagenhydroxyapatite composite nanofibers for bone tissue engineering
생체재료학회지
2017 .01
-
가토 두개골에 이식한 다양한 형태의 자가골에 의한 골성 회복 양상 비교 평가
대한구강악안면외과학회지
2008 .01
-
Comparative study of new bone formation capability of zirconia bone graft material in rabbit calvarial
The Journal of Advanced of Prosthodontics
2018 .01
-
Characterization of Dexamethasone-eluting PLGA Films Coated on Capsular Tension Ring to Prevent Posterior Capsule Opacification
Biomolecules & Therapeutics(구 응용약물학회지)
2008 .01
-
골수내천공을 동반한 골유도재생술시 법랑기질유도체의 효과
Journal of Periodontal & Implant Science
2004 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0