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논문 기본 정보

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학술저널
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대한치과보철학회 The Journal of Advanced of Prosthodontics The Journal of Advanced of Prosthodontics 제7권 제2호
발행연도
2015.1
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172 - 177 (6page)

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PURPOSE. The purpose of this study was to evaluate cell toxicity due to ion release caused by galvanic corrosion as a result of contact between base metal and titanium. MATERIALS AND METHODS. It was hypothesized that Nickel (Ni)-Chromium (Cr) alloys with different compositions possess different corrosion resistances when contacted with titanium abutment, and therefore in this study, specimens (10×10×1.5 mm) were fabricated using commercial pure titanium and 3 different types of Ni-Cr alloys (T3, Tilite, Bella bond plus) commonly used for metal ceramic restorations. The specimens were divided into 6 groups according to the composition of Ni-Cr alloy and contact with titanium. The experimental groups were in direct contact with titanium and the control groups were not. After the samples were immersed in the culture medium - Dulbecco’s modified Eagle’s medium[DMEM] for 48 hours, the released metal ions were detected using inductively coupled plasma mass spectrometer (ICP-MS) and analyzed by the Kruskal-Wallis and Mann-Whitney test (P<.05). Mouse L-929 fibroblast cells were used for cell toxicity evaluation. The cell toxicity of specimens was measured by the 3-{4,5-dimethylthiazol-2yl}-2,5-diphenyltetrazolium bromide (MTT) test. Results of MTT assay were statistically analyzed by the two-way ANOVA test (P<.05). Post-hoc multiple comparisons were conducted using Tukey’s tests. RESULTS. The amount of metal ions released by galvanic corrosion due to contact between the base metal alloy and titanium was increased in all of the specimens. In the cytotoxicity test, the two-way ANOVA showed a significant effect of the alloy type and galvanic corrosion for cytotoxicity (P<.001). The relative cell growth rate (RGR) was decreased further on the groups in contact with titanium (P<.05). CONCLUSION. The release of metal ions was increased by galvanic corrosion due to contact between base metal and titanium, and it can cause adverse effects on the tissue around the implant by inducing cytotoxicity.
#Galvanic corrosion #Nickel-Chromium #Dental alloy #Titanium abutment #Cytotoxicity #Ion release

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참고문헌 (27)

참고문헌 신청
/ 1987 / American Dental Association status report on the occurrence of galvanic corrosion in the mouth and its potential effects. Council on Dental Materials, Instruments, google schola Al-Hiyasat AS / 2003 / An investigation of the cytotoxic effects of dental casting alloys / Int J Prosthodont 16 : 8 ~ 12 google schola Baran GR / 1983 / The metallurgy of Ni-Cr alloys for fixed prosthodontics / J Prosthet Dent 50 : 639 ~ 650 google schola Brune D / 1986 / Metal release from dental biomaterials / Biomaterials 7 : 163 ~ 175 google schola Bumgardner JD / 1993 / Surface analysis of nickel-chromium dental alloys / Dent Mater 9 : 252 ~ 259 google schola

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