지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제13권 제1호
- 발행연도
- 2015.1
- 수록면
- 103 - 108 (6page)
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초록· 키워드
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Objective: The primary goals of the present study were to assess intellectual function in participants with schizophrenia or bipolar disorder (BD) and to investigate the relationships between cognitive decline and the severity of each type of psychopathology.
Methods: The present study included 51 patients with schizophrenia and 42 with BD who were recruited from the psychiatry outpatient clinic of Jeju University Hospital between March 2011 and March 2014. The Korean Wechsler Adult Intelligence Scale (K-WAIS) was administered to each of the 93 participants, and they were categorized into two groups based on their current intelligence quotient (IQ) and their estimated premorbid IQ: severely impaired group (SIG) and mildly impaired group (MIG). The Minnesota Multiple Personality Inventory (MMPI) and the Brief Psychiatric Rating Scale (BPRS) were used to assess psychopathology.
Results: The SIG schizophrenia participants exhibited significantly higher scores on the frequent (F) and schizophrenia (Sc) subscales of the MMPI, but significantly lower scores on the correction (K) and psychopathic deviate (Pd) subscales compared with the MIG schizophrenia participants. Furthermore, the BPRS scores were significantly higher in the SIG schizophrenia participants relative to the MIG schizophrenia participants. The SIG BD participants had significantly higher F, masculinity-femininity (Mf), paranoia (Pa), and Sc but significantly lower Pd scores compared with the MIG BD participants.
Conclusion: The present findings revealed a significant discrepancy between the estimated premorbid levels of cognitive function and current cognitive function in participants with schizophrenia or BD. Moreover, this discrepancy was correlated with severity of psychopathology in both groups.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Albus M. / 1996 / Contrasts in neuropsychological test profile between patients with first-episode schizophrenia and first-episode affective disorders / Acta Psychiatr Scand
Altshuler L. / 2007 / Executive function and employment status among veterans with bipolar disorder / Psychiatr Serv 58 : 1441 ~ 1447
Bell M. / 1992 / The Positive and Negative Syndrome Scale and the Brief Psychiatric Rating Scale. Reliability, comparability, and predictive validity / J Nerv Ment Dis 180 :
Bora E. / 2015 / Developmental trajectory of cognitive impairment in bipolar disorder : Comparison with schizophrenia / Eur Neuropsychopharmacol 25 : 158 ~ 168
Demidenko N. / 2004 / MMPI as a measure of subthreshold and residual psychopathology among the offspring of lithium responsive and non-responsive bipolar parents / Bipolar D
Altshuler L. / 2007 / Executive function and employment status among veterans with bipolar disorder / Psychiatr Serv 58 : 1441 ~ 1447
Bell M. / 1992 / The Positive and Negative Syndrome Scale and the Brief Psychiatric Rating Scale. Reliability, comparability, and predictive validity / J Nerv Ment Dis 180 :
Bora E. / 2015 / Developmental trajectory of cognitive impairment in bipolar disorder : Comparison with schizophrenia / Eur Neuropsychopharmacol 25 : 158 ~ 168
Demidenko N. / 2004 / MMPI as a measure of subthreshold and residual psychopathology among the offspring of lithium responsive and non-responsive bipolar parents / Bipolar D
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