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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 380 - 383 (4page)
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Dear Editor, Post-transplant lymphoproliferative disorders (PTLDs) are a rare group of atypical lymphoid proliferations that develop as a result of immunosuppression in recipients of solid organ transplant or allogeneic hematopoietic stem cell transplant. According to the 4th edition of the World Health Organization Classification of Tumors of Haematopoietic and Lymphoid Tissues, PTLD is further divided into four categories on the basis of the histologic, immunophenotypic, and genetic characteristics: (1) early lesions consisting of plasmacytic hyperplasia and infectious mononucleosis–like, (2) polymorphic PTLD, (3) monomorphic PTLD, further classified according to the respective lymphoid or plasmacytic neoplasm they resemble in immunocompetent individuals, and (4) classic Hodgkin lymphoma-type PTLD [1]. The diagnosis and classification of PTLD are currently based on histologic criteria; hence, cytogenetic abnormalities have not been fully investigated. We report the first case of a monomorphic PTLD, diffuse large B-cell lymphoma (DLBCL) infiltrating spleen and bone marrow (BM) with t(3;6)(q27;p22) involving BCL6.
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참고문헌 (10)
참고문헌 신청
Swerdlow SH / 2008 / WHO classification of tumours of haematopoietic and lymphoid tissues / IARC :8~350
Djokic M / 2006 / Post-transplant lymphoproliferative disorder subtypes correlate with different recurring chromosomal abnormalities / Genes Chromosomes Cancer 45:313~318
Lo Coco F / 1994 / Rearrangements of the BCL6 gene in diffuse large cell non-Hodgkin’s lymphoma / Blood 83:1757~1759
Akasaka T / 1997 / A recurring translocation, t(3;6)(q27;p21), in non-Hodgkin’s lymphoma results in replacement of the 5’ regulatory region of BCL6 with a novel H4 histone gene / Cancer Res 57:7~12
Akasaka H / 2000 / Molecular anatomy of BCL6 translocations revealed by long-distance polymerase chain reaction-based assays / Cancer Res 60:2335~2341
Djokic M / 2006 / Post-transplant lymphoproliferative disorder subtypes correlate with different recurring chromosomal abnormalities / Genes Chromosomes Cancer 45:313~318
Lo Coco F / 1994 / Rearrangements of the BCL6 gene in diffuse large cell non-Hodgkin’s lymphoma / Blood 83:1757~1759
Akasaka T / 1997 / A recurring translocation, t(3;6)(q27;p21), in non-Hodgkin’s lymphoma results in replacement of the 5’ regulatory region of BCL6 with a novel H4 histone gene / Cancer Res 57:7~12
Akasaka H / 2000 / Molecular anatomy of BCL6 translocations revealed by long-distance polymerase chain reaction-based assays / Cancer Res 60:2335~2341
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