지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 103 - 107 (5page)
이용수
초록· 키워드
오류제보하기
Objective: To determine the effects of the antiresorptive agent bisphosphonate in hemiplegic patients with CRPS and to compare its effects to standard steroid pulse therapy.
Method: Thirteen randomly selected hemiplegic patients diagnosed with CRPS received bisphosphonate therapy which consisted of intravenous pamidronate injection of a total cumulative dose of 180 mg in one week. Eleven hemiplegic patients with CRPS received the standard 2-week steroid pulse therapy. Clinical assessments were made for temperature, pain score, volumetry and circumference of both the third digit and wrist. All assessments were carried out twice; before the initiation of therapy and two weeks after pamidronate or steroid therapy.
Results: The steroid group showed statistical improvement in pain (p=0.039), total hand volume(p=0.006) wrist (p= 0.007) and 3rd digit (p=0.003) circumference. The pamidronate group showed statistical improvement in pain (p=0.011), wrist (p=0.043) and 3rd digit (p=0.021) circumference; however no statistical improvement was observed in total hand volume (p=0.767). Neither group showed any statistical significance in temperature change.
Conclusion: Pamidronate therapy may be an alternative method in managing CRPS in hemiplegic patients with multiple medical comorbidities who are not eligible to receive the conventional steroid therapy.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Adami S / 1997 / Bisphophonate therapy of reflex sympathetic dystrophy syndrome / Ann Rheum Dis 56 : 201 ~ 204
Breuer B / 2008 / An open-label pilot trial of ibandronate for complex regional pain syndrome / Clin J Pain 24 : 685 ~ 689
Cooke ED / 1989 / Reflex sympathetic dystrophy (algoneurodystrophy): temperature studies in the upper limb / Br J Rheumatol 28 : 399 ~ 403
David SW / 1977 / Shoulder-hand syndrome in a hemiplegic population: a 5-year retrospective study / Arch Phys Med Rehabil 58 : 353 ~ 356
Delay-Goyet P / 1991 / Relative involvement of substance P and CGRP mechanisms in antidromic vasodilation in the rat skin / Acta Physiol Scand 146 : 537 ~ 538
Breuer B / 2008 / An open-label pilot trial of ibandronate for complex regional pain syndrome / Clin J Pain 24 : 685 ~ 689
Cooke ED / 1989 / Reflex sympathetic dystrophy (algoneurodystrophy): temperature studies in the upper limb / Br J Rheumatol 28 : 399 ~ 403
David SW / 1977 / Shoulder-hand syndrome in a hemiplegic population: a 5-year retrospective study / Arch Phys Med Rehabil 58 : 353 ~ 356
Delay-Goyet P / 1991 / Relative involvement of substance P and CGRP mechanisms in antidromic vasodilation in the rat skin / Acta Physiol Scand 146 : 537 ~ 538
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