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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 431 - 439 (9page)
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Background: Several latest guidelines and consensus statements from Europe and the United States specify that there is no need for fasting prior to routine lipid tests. However, the latest Chinese guidelines still recommend fasting tests owing to a lack of local evidence. This study aimed to investigate postprandial lipid concentrations and daytime biological variation of lipids in a healthy Chinese population. Methods: Venous blood samples were collected from 41 ostensibly healthy Chinese volunteers at five time points during the day (06:30, 09:00, 12:00, 15:00, and 18:30). The same batch of reagents was used to determine lipid concentrations. A nested ANOVA was performed to calculate within-subject biological variation (CVI) and between-subject biological variation (CVG). Results: Postprandial concentrations of triglyceride were higher than fasting concentrations, with the maximum change occurring at 12:00 (0.5 hours after lunch, 0.21±0.65 mmol/L difference). The daytime biological variation of triglycerides was relatively high (CVI=25%, CVG=35.9%). The postprandial concentrations of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, apolipoprotein A1, and apolipoprotein B were mostly lower than the fasting concentrations, and their daytime biological variations were relatively low (CVI=2.4–4.4%, CVG=11.8–18.7%).
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참고문헌 (35)
참고문헌 신청
Catapano AL / 2016 / 2016 ESC/EAS guidelines for the management of dyslipidaemias / Eur Heart J 37:2999~3058
Joint Committee for Revising the Chinese Guidelines on Prevention / 2016 / Chinese guidelines on prevention and treatment of dyslipidemia in adults (Revised in 2016) (in Chinese) / Chin J Cardiol 44:833~853
Nordestgaard BG / 2016 / Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points-a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine / Eur Heart J 37:1944~1958
Rifai N / 2016 / Nonfasting sample for the determination of routine lipid profile: is it an idea whose time has come? / Clin Chem 62:428~435
Farukhi Z / 2016 / Re-assessing the role of non-fasting lipids; a change in perspective / Ann Transl Med 4:431
Joint Committee for Revising the Chinese Guidelines on Prevention / 2016 / Chinese guidelines on prevention and treatment of dyslipidemia in adults (Revised in 2016) (in Chinese) / Chin J Cardiol 44:833~853
Nordestgaard BG / 2016 / Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points-a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine / Eur Heart J 37:1944~1958
Rifai N / 2016 / Nonfasting sample for the determination of routine lipid profile: is it an idea whose time has come? / Clin Chem 62:428~435
Farukhi Z / 2016 / Re-assessing the role of non-fasting lipids; a change in perspective / Ann Transl Med 4:431
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