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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.7
- 수록면
- 41 - 55 (15page)
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초록· 키워드
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Background: High concentrations of mercury intake from seafood are known to cause various side effects in humans, including on the nervous system. Various studies have reported the effects of mercury concentrations in humans; however, the association between dyslipidemia, a cardiovascular disease risk factor, and mercury remains controversial. Therefore, this study aimed to investigate the association between mercury accumulation and cholesterol concentrations in a Korean population.
Methods: We analyzed data of a sample of 3,228 respondents obtained from the Korean National Environmental Health Survey cycle 3, surveyed between 2015 and 2017, to determine how lipid profiles changed according to the blood mercury concentrations (BHg) and urine mercury concentrations (UHg). Multiple regression analysis was used to determine the effects of mercury concentrations among various factors affecting blood cholesterol levels.
Results: The arithmetic mean (AM) of BHg was 2.91 (2.81–3.02) μg/L, and the geometric mean (GM) was 2.71 (2.59–2.85) μg/L. The AM of UHg was 0.52 (0.48–0.56) μg/L, and the GM was 0.35 (0.33–0.38) μg/L. Lipid profiles were more related to the BHg than to the UHg. Total cholesterol (total-C), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) levels increased significantly as BHg increased in males, and total-C, triglyceride, and LDL-C levels increased significantly in females. Multiple regression analysis indicated that BHg were significantly associated with total-C, HDL-C, and LDL-C levels.
Conclusions: We found an association between mercury exposure and the risk of dyslipidemia; however, further studies are required to elucidate a causal association.
Methods: We analyzed data of a sample of 3,228 respondents obtained from the Korean National Environmental Health Survey cycle 3, surveyed between 2015 and 2017, to determine how lipid profiles changed according to the blood mercury concentrations (BHg) and urine mercury concentrations (UHg). Multiple regression analysis was used to determine the effects of mercury concentrations among various factors affecting blood cholesterol levels.
Results: The arithmetic mean (AM) of BHg was 2.91 (2.81–3.02) μg/L, and the geometric mean (GM) was 2.71 (2.59–2.85) μg/L. The AM of UHg was 0.52 (0.48–0.56) μg/L, and the GM was 0.35 (0.33–0.38) μg/L. Lipid profiles were more related to the BHg than to the UHg. Total cholesterol (total-C), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) levels increased significantly as BHg increased in males, and total-C, triglyceride, and LDL-C levels increased significantly in females. Multiple regression analysis indicated that BHg were significantly associated with total-C, HDL-C, and LDL-C levels.
Conclusions: We found an association between mercury exposure and the risk of dyslipidemia; however, further studies are required to elucidate a causal association.
목차
ABSTRACT
BACKGROUND
METHODS
RESULTS
DISCUSSION
CONCLUSIONS
REFERENCES
참고문헌 (55)
참고문헌 신청
You CH / 2012 / The relationship between the fish consumption and blood total/methyl-mercury concentration of costal area in Korea / Neurotoxicology 33(4):676~682
김진아 / 2013 / 서울시 유통 다랑어류, 새치류 및 심해성 어류의 총수은 및 메틸수은 축적에 대한 고찰 / 한국식품과학회지 45(3):376~381
김문경 / 2012 / Fate and Transport of Mercury in Environmental Media and Human Exposure / 예방의학회지 45(6):335~343
Choi W / 2017 / Exposure to environmental chemicals among Korean adults-updates from the second Korean National Environmental Health Survey(2012–2014) / Int J Hyg Environ Health 220(2 Pt A):29~35
Yoshizawa K / 2002 / Mercury and the risk of coronary heart disease in men / N Engl J Med 347(22):1755~1760
김진아 / 2013 / 서울시 유통 다랑어류, 새치류 및 심해성 어류의 총수은 및 메틸수은 축적에 대한 고찰 / 한국식품과학회지 45(3):376~381
김문경 / 2012 / Fate and Transport of Mercury in Environmental Media and Human Exposure / 예방의학회지 45(6):335~343
Choi W / 2017 / Exposure to environmental chemicals among Korean adults-updates from the second Korean National Environmental Health Survey(2012–2014) / Int J Hyg Environ Health 220(2 Pt A):29~35
Yoshizawa K / 2002 / Mercury and the risk of coronary heart disease in men / N Engl J Med 347(22):1755~1760
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UCI(KEPA) : I410-ECN-0101-2020-517-001091490