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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 73 - 75 (3page)
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Dear Editor, Stenotrophomonas maltophilia has received considerable attention owing to its high infection rate and resistance to multiple antibiotic classes [1].Trimethoprim/sulfamethoxazole (SXT) is the recommended first-line therapy for S. maltophilia infection; however, resistance ratesto SXT of S. maltophilia have increased worldwide; in Anhui province of China, the resistance rate has increased from 10% to 40% over the past five years [2]. Accordingly, it is important to study the mechanisms underlying SXT resistance and prevent the spread of resistance. We found that sul1 in combination with sul2 confers high-level resistance to SXT; sul1 was always found as part of the 3´ end of the class 1 integron, in Anhui province [3]; however, no association between sul2 and integrons was found.
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참고문헌 (7)
참고문헌 신청
Brooke JS / 2012 / Stenotrophomonas maltophilia: an emerging global opportunistic pathogen / Clin Microbiol Rev 25:2~41
Hu LF / 2014 / Susceptibility of Stenotrophomonas maltophilia clinical strains in China to antimicrobial combinations / J Chemother 26:282~286
Hu LF / 2011 / Stenotrophomonas maltophilia resistance to trimethoprim/sulfamethoxazole mediated by acquisition of sul and dfrA genes in a plasmid-mediated class 1 integron / Int J Antimicrob Agents 37:230~234
Clinical and Laboratory Standards Institute / 2013 / Performance standards for antimicrobial susceptibility testing / CLSI
Toleman MA / 2007 / Global emergence of trimethoprim/sulfamethoxazole resistance in Stenotrophomonas maltophilia mediated by acquisition of sul genes / Emerg Infect Dis 13:559~565
Hu LF / 2014 / Susceptibility of Stenotrophomonas maltophilia clinical strains in China to antimicrobial combinations / J Chemother 26:282~286
Hu LF / 2011 / Stenotrophomonas maltophilia resistance to trimethoprim/sulfamethoxazole mediated by acquisition of sul and dfrA genes in a plasmid-mediated class 1 integron / Int J Antimicrob Agents 37:230~234
Clinical and Laboratory Standards Institute / 2013 / Performance standards for antimicrobial susceptibility testing / CLSI
Toleman MA / 2007 / Global emergence of trimethoprim/sulfamethoxazole resistance in Stenotrophomonas maltophilia mediated by acquisition of sul genes / Emerg Infect Dis 13:559~565
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