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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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This paper presents a paper-based concentration gradient chip to analyze colorimetric glucose assay. The paper-based concentration gradient chip was fabricated through a wax patterning technique that can design the fluidic channel by selectively printing hydrophobic and hydrophilic areas. Afterwards, glucose and dilution solutions were loaded into the inlet of a concentration gradient chip and each solution was then mixed sequentially at mixing channel.
Finally, concentration gradient was formed at each outlet of the chip. To measure the glucose concentration of the solution in outlets, we conducted colorimetric glucose assay with fixed concentration of glucose solution (0, 5, 10, 15 and 20 mM) and obtained normalized intensity. Subsequently, glucose concentrations of the outlets were calculated by substituting the normalized intensity to linear regression function based on the normalized intensity of fixed glucose concentration. Finally, the concentration gradient of glucose was formed on the chip with the result of colorimetric assay. The concentration gradient paper chip has the potential to accurately analyze unknown glucose concentration.
목차
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참고문헌 (13)
참고문헌 신청
A. Martinez / 2010 / Diagnostics for the Developing World : Microfluidic Paper-Based Analytical Devices / Anal. Chem 82(1):3~10
A. Martinez / 2007 / Patterned Paper as a Platform for Inexpensive, Low-Volume, Portable Bioassays / Angew. Chem 119(8):1340~1342
A. Martinez / 2008 / Simple Telemedicine for Developing Regions : Camera Phones and Paper-Based Microfluidic Devices for Real-Time, Off-Site Diagnosis / Anal. Chem 80(10):3699~3707
A. Martinez / 2008 / Three-dimensional microfluidic devices fabricated in layered paper and tape / Proc. Natl. Acad. Sci. U.S.A 105(50):19606~19611
W. Dungchai / 2010 / Use of multiple colorimetric indicators for paper-based microfluidic devices / Anal. Chim. Acta 674(2):227~233
A. Martinez / 2007 / Patterned Paper as a Platform for Inexpensive, Low-Volume, Portable Bioassays / Angew. Chem 119(8):1340~1342
A. Martinez / 2008 / Simple Telemedicine for Developing Regions : Camera Phones and Paper-Based Microfluidic Devices for Real-Time, Off-Site Diagnosis / Anal. Chem 80(10):3699~3707
A. Martinez / 2008 / Three-dimensional microfluidic devices fabricated in layered paper and tape / Proc. Natl. Acad. Sci. U.S.A 105(50):19606~19611
W. Dungchai / 2010 / Use of multiple colorimetric indicators for paper-based microfluidic devices / Anal. Chim. Acta 674(2):227~233
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