메뉴 건너뛰기
Library Notice
Institutional Access
If you certify, you can access the articles for free.
Check out your institutions.
ex)Hankuk University, Nuri Motors
Log in Register Help KOR
Subject
Humanities
General Humanities History Philosophy Religious Studies Linguistics and Literature Other Humanities
Social science
General Social Science Business Management Tourism Education Military Science Library and Information Science Law Sociology Journalism and Media Studies Psychological Science Political Science and Diplomacy Geography Public Administration Economics International Trade Anthropology Other Social Science
Natural science
General Natural Science Physics Biology Life Sciences Mathematics/Statistics Astronomy Earth Science Chemistry Other Natural Science
Engineering
General Engineering Architectural Engineering Mechanical Engineering Industrial Engineering Material/Energy Engineering Electrical and Electronic Engineering Marine and Ocean Engineering Chemical Engineering Computer Science Other Engineering
Medical science
General Medical Science Nursing Science Veterinary Pharmacy Traditional Korean Medicine Basic Medicine Clinical Medicine Other Medicine
Agriculture and Fishery
General Agriculture and Fishery Agriculture Fishery Science Food Science Forestry Animal Husbandry Marine Transportation Studies Other Agriculture and Fishery
Art and Kinesiology
General Arts Design Fine Arts Cosmetology Photography Music Fashion Kinesiology Performing Media Arts Other Arts and Kinesiology
Interdisciplinary Studies
Interdisciplinary Research Science and Technology Studies Brain and Cognitive Science Technology Policy Other Interdisciplinary Studies

KOR

The Association Between Oxidative Stress and Depressive Symptom Scores in Elderly Population: A Repeated Panel Study
Recommendations
Search

논문 기본 정보

Type
Academic journal
Author
Journal
대한예방의학회 예방의학회지 예방의학회지 제49권 제5호 KCI Accredited Journals
Published
2016.1
Pages
260 - 274 (15page)

Usage

cover
The Association Between Oxidative Stress and Depressive Symptom Scores in Elderly Population: A Repeated Panel Study
Ask AI
Recommendations
Search

Abstract· Keywords

Report Errors
Objectives: Previous epidemiological studies about oxidative stress and depression are limited by hospital-based case-control design, single-time measurements of oxidative stress biomarkers, and the small number of study participants. Therefore, in this study, we analyzed the association between biomarker of oxidative stress and depressive symptom scores using repeatedly measured panel data from a community-dwelling elderly population. Methods: From 2008 to 2010, a total of 478 elderly participants residing in Seoul, Korea, were evaluated three times. Participants underwent the Korean version of the Short Form Generic Depression Scale (SGDS-K) test for screening depression, and urinary malondialdehyde (MDA) levels were measured as an oxidative stress biomarker. We used a generalized estimating equation with a compound symmetry covariance structure to estimate the effects of oxidative stress on depressive symptom scores. Results: A two-fold increase in urinary MDA concentration was significantly associated with a 33.88% (95% confidence interval [CI], 21.59% to 47.42%) increase in total SGDS-K scores. In subgroup analyses by gender, a two-fold increase in urinary MDA concentration was significantly associated with increased SGDS-K scores in both men and women (men: 30.88%; 95% CI, 10.24% to 55.37%; women: 34.77%; 95% CI, 20.09% to 51.25%). In bivariate analysis after an SGDS-K score ≥8 was defined as depression, the third and the fourth urinary MDA quartiles showed a significantly increased odds ratio(OR) of depression compared to the lowest urinary MDA quartile (third quartile OR, 6.51; 95% CI, 1.77 to 24.00; fourth quartile OR, 7.11; 95% CI, 1.99 to 25.42). Conclusions: Our study suggests a significant association between oxidative stress and depressive symptoms in the elderly population.
#Depression #Depressive disorder #Oxidative stress #Malondialdehyde #Aged

Contents

No content found

References (40)

Add References
Marcus M / WHO Department of Mental Health and Substance Abuse. Depression: a global public health concern google schola Fiske A / 2009 / Depression in older adults / Annu Rev Clin Psychol 5:363~389 google schola Reeve J / 2008 / Revisiting depression in palliative care settings: the need to focus on clinical utility over validity / Palliat Med 22(4):383~391 google schola Michel TM / 2012 / The role of oxidative stress in depressive disorders / Curr Pharm Des 18(36):5890~5899 google schola Hovatta I / 2010 / Oxidative stress in anxiety and comorbid disorders / Neurosci Res 68(4):261~275 google schola

Recommendations

It is an article recommended by DBpia according to the article similarity. Check out the related articles!

Related Authors

Recently viewed articles

Technology Relation for Patent of Technology Transfer based on IPC Code
Kyoungrae Lee, Junseok Lee, Sangsung ParkKorean Institute of Intelligent Systems2015.10
 Design and Implementation of Automatic Marking System for a Subjectivity Problem of the Program
Eunmi Jung, Misun Choi, Jaechang ShimKorea Multimedia Society2009.05
 Evaluation of Perception and Foodservice Satisfaction of Free School Meals by Elementary School Students in Busan
Eun Ryung Jang, Hee Sun Choi, Eun Soon LyuThe korean Society of Food Science and Nutrition2016.12
 Chinese Painting from Dewey’s Aesthetic Perspective
IlHee Hong2022.12

Comments(0)

0

Write first comments.