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Analysis of the Clinicopathological Characteristics of Gastric Cancer in Extremely Old Patients
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논문 기본 정보

Type
Academic journal
Author
Journal
대한암학회 Cancer Research and Treatment Cancer Research and Treatment 제49권 제1호 KCI Accredited Journals
Published
2017.1
Pages
204 - 212 (9page)

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Analysis of the Clinicopathological Characteristics of Gastric Cancer in Extremely Old Patients
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Purpose Gastric cancer is the third-leading cause of cancer-related death in Korea. As the Korean population is ageing, the number of extremely old patients with this disease is increasing. This study examined the clinicopathological characteristics of gastric cancer in extremely old (over 85 years) patients who received treatment or conservative observations and compared the treatment outcomes according to the treatment modality. Materials and Methods A total of 170 patients over 85 years of age were diagnosed with gastric cancer. Of these, 81 underwent treatment for gastric cancer and 89 received conservative observations. The clinicopathological characteristics of the treatment and conservative groups were compared. Results The mean age of the patients was 86.5 years. The conservative group included significantly more patients with older ages, macroscopically advanced cancer and upper-middle located cancer. The overall survival rate of the treatment group was significantly higher than that of the conservative group. The disease-specific mortality rate was significantly lower in the treatment group than in the conservative group. Multivariate analysis revealed the clinical course, alarm sign, and macroscopic classification to be independent prognosis factors. Conclusion By itself, the chronological age should not be used as a strategy to determine whether treatment will be administered for gastric cancer. Patients who have early gastric cancer or lowerrisk preexisting comorbidities should not be discouraged from treatment, even if they are older than 85 years.
#Oldest old #Aged #Stomach neoplasms #Therapy

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Arai T / 2004 / Pathologic characteristics of gastric cancer in the elderly : a retrospective study of 994 surgical patients / Gastric Cancer 7 : 154 ~ 159 google schola Benhamiche AM / 1997 / Time trends in diagnostic strategy, treatment, and prognosis of gastric cancer in the elderly : a population based study / Eur J Cancer Prev 6 : 71 ~ google schola Choi KS / 2015 / Effect of endoscopy screening on stage at gastric cancer diagnosis : results of the National Cancer Screening Programme in Korea / Br J Cancer 112 : 608 ~ 61 google schola Damhuis RA / 1995 / The influence of age on resection rates and postoperative mortality in 2773 patients with gastric cancer / Eur J Cancer 31A : 928 ~ 931 google schola Eguchi T / 2003 / Mortality for gastric cancer in elderly patients / J Surg Oncol 84 : 132 ~ 136 google schola

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