청원군 일개 면에서 산발적으로 신고한 세균성이질 집단 발병 역학조사

강종원; 구자설; 김종숙; 황의경; 김준영; 이용제; 이복권

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자료유형: 학술저널

저자정보: 강종원 구자설 김종숙 황의경 김준영 이용제 이복권

저널정보: 대한예방의학회 예방의학회지 예방의학회지 제38권 제2호

발행연도: 2005.1

수록면: 182 - 188 (7page)

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Objectives: This study was undertaken to investigate the source of infection and mode of transmission of shigellosis, which occurred sporadically among residents and students in a subcounty of Cheongwon county, Chungbuk province, Korea, from June 4 to July 3 2003. Methods: 692 subjects completed a questionnaire and provided a swab for microbiological examinations,and 7 environmental specimens were examined for bacterial organisms. PFGE (pulsed-field gel electrophoresis) and fingerprinting were performed to find the genetic relationship among the temporally associated sporadic isolates. Results: A total of 29 patients had symptoms consistent with the case definition, with 13 confirmed and 16 suspected cases. The frequency of diarrhea was 6 times or more a day (80.8%), with a duration of 1 to 4 days (88.5%) in most cases. The most common symptoms accompanying the diarrhea were fever (80.9%) followed by abdominal pain (76.9%), headache (65.4%), chill (61.5%), vomiting (46.2%) and tenesmus (15.4%). The epidemic curve was characteristic of a person-to-person transmission. The PFGE and fingerprinting demonstrated identical or similar DNA patterns among the 3 Shigella sonnei isolates (A51, A53 and A61 types) found in this outbreak. Conclusion: A genetically identical strain of S. sonnei was estimated to be the cause of this outbreak, and the mode of transmission was most likely person-to-person.

#Epidemiology #Transmission #Shigellosis #Pulsed-field gel electrophoresis

참고문헌 (10)

참고문헌 신청

Butler T, / 2004 / Shigellosis. In:Goldman L, Ausiello D. editors. Cecil textbookof medicine, 22nd ed. : 1852 ~ 1855

Chun JH / 2001 / Molecular typing of Shigella sonneiisolated in Korea using PFGE The Report ofNational Institute of Health 2001 38 : 5 ~ 17

Cohen D / lancet1991 / Reduction oftransmission of shegellosis by control ofhouseflies : 993 ~ 7

DuPont HL / 2000 / Principles andpractice of Infectious disease : 2363 ~ 8

Goering RV / jclinmicrobiol1995 / Interpreting chromosomalDNA restriction patterns produced by pulsedfieldgel electrophoresis criteria for bacterialstrain typing 33 (9) : 223

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