지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 189 - 196 (8page)
이용수
초록· 키워드
오류제보하기
Purpose The objective of this study was to evaluate external beam radiotherapy (EBRT) in lung cancerpatients who suffer from airway obstruction.
Materials and MethodsMedical data of 95 patients with a lung mass that obstructed the airway and received EBRTfor it were analyzed. Fifty-nine patients (62.1%) had non-small cell lung cancer and 36patients (37.9%) had small cell lung cancer. Radiotherapy was given at 8 to 45 Gy (median,30 Gy) in 1 to 15 fractions (median, 10 fractions). The response to EBRT was assessedthrough changes in radiographic findings and/or subjective symptoms between before andafter EBRT. The median follow-up duration was 124 days. The primary end point was theairway-obstruction resolving rate after EBRT. The secondary end points were patient survivaland toxic effects of EBRT.
ResultsImprovement of airway obstruction after EBRT on chest X-ray was achieved in 75 of 95patients (78.9%). The median time for resolving the radiologic findings and/or symptomsof airway obstruction after EBRT was 7 days (range, 1 to 76 days). The 1-year survival ratewas significantly higher in responders than non-responders (12.5% vs. 0.0%, p < 0.001).
The biologically effective dose of 39 Gy/=10 (p < 0.01) and the longest obstructive lesionof < 6 cm (p=0.04) were significantly associated with a good response to EBRT in resolvingthe airway obstruction. No one had grade 3 or higher acute and chronic toxicities.
ConclusionEBRT is an effective treatment in relieving airway obstruction without severe toxicities inlung cancer patients.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
/ 1991 / Inoperable non-small-cell lung cancer (NSCLC): a Medical Research Council randomised trial of palliative radiotherapy with two fractions or ten fractions. Report to
/ 1992 / A Medical Research Council (MRC) randomised trial of palliative radiotherapy with two fractions or a single fraction in patients with inoperable non-small-cell lung
Arriagada R / 2004 / Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer / N Engl J Med 350 : 351 ~ 360
Aumont-le Guilcher M / 2011 / High-dose-rate brachytherapy for non-small-cell lung carcinoma : a retrospective study of 226patients / Int J Radiat Oncol Biol Phys 79 : 1112
Carroll M / 1986 / Prospective evaluation of a watch policy in patients with inoperable non-small cell lung cancer / Eur J Cancer Clin Oncol 22 : 1353 ~ 1356
/ 1992 / A Medical Research Council (MRC) randomised trial of palliative radiotherapy with two fractions or a single fraction in patients with inoperable non-small-cell lung
Arriagada R / 2004 / Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer / N Engl J Med 350 : 351 ~ 360
Aumont-le Guilcher M / 2011 / High-dose-rate brachytherapy for non-small-cell lung carcinoma : a retrospective study of 226patients / Int J Radiat Oncol Biol Phys 79 : 1112
Carroll M / 1986 / Prospective evaluation of a watch policy in patients with inoperable non-small cell lung cancer / Eur J Cancer Clin Oncol 22 : 1353 ~ 1356
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Treatment outcomes after adjuvant radiotherapy following surgery for patients with stage I endometrial cancer
Radiation oncology journal : ROJ
2016 .01
-
The role of adjuvant external beam radiation therapy for papillary thyroid carcinoma invading the trachea
Radiation oncology journal : ROJ
2017 .01
-
Treatment of Retinoblastoma: The Role of External Beam Radiotherapy
Yonsei Medical Journal
2015 .01
-
Three Cases of Pierre Robin Sequence with Upper Airway Obstruction Relieved by Nasopharyngeal Airway Insertion
Neonatal medicine
2019 .01
-
Characteristics of Obstructive Sleep Apnea Patients With a Low Body Mass Index: Emphasis on the Obstruction Site Determined by Drug-Induced Sleep Endoscopy
Clinical and Experimental Otorhinolaryngology
2020 .01
-
Value of combined adjuvant chemotherapy and radiation on survival for stage III uterine cancer: is less radiation equal to more?
Journal of Gynecologic Oncology
2018 .01
-
Tongue-lip adhesion in Pierre Robin sequence
대한구강악안면외과학회지
2016 .01
-
음식물에 의한 후두화상 후 발생한 기도폐쇄 1예
대한이비인후-두경부외과학회지
2015 .01
-
Pharmacodynamic Estimate of Propofol-Induced Sedation and Airway Obstruction Effects in Obstructive Sleep Apnea-Hypopnea Syndrome
Yonsei Medical Journal
2015 .01
-
Popular websites as a source of misinformation on first aid in foreign body airway obstruction
Clinical and Experimental Emergency Medicine
2024 .09
-
Endoscopic Management of Benign Colonic Obstruction and Pseudo-Obstruction
Clinical Endoscopy
2020 .01
-
Analysis of Once-Daily Thoracic Radiotherapy Dose According to the Underlying Lung Disease in Patients with Limited-Stage Small Cell Lung Cancer Undergoing Concurrent Chemoradiotherapy
Cancer Research and Treatment
2023 .01
-
Airway obstruction during general anesthesia in a premature infant suspecting bronchospasm and/or airway malacia -A case report-
Anesthesia and Pain Medicine
2017 .01
-
Ex utero intrapartum treatment procedure in two fetuses with airway obstruction
Obstetrics & Gynecology Science
2018 .01
-
선천성 상기도폐쇄증후군에서의 분만 중 자궁 외 치료 1예
임상이비인후과
2017 .12
-
심경부감염으로 인한 급성 기도폐쇄 환자에서 고유량 비강 캐뉼라 보조 기관절개술로 기도를 확보한 1례
임상이비인후과
2021 .01
-
Brachytherapy utilization rate and effect on survival in cervical cancer patients in Korea
Journal of Gynecologic Oncology
2021 .11
-
Surgical Management of Mechanical Obstruction
대한외과학회 학술대회 초록집
2019 .10
-
Intermittent Airway Obstruction Caused by a Laryngeal Cyst Masquerading as Asthma Attacks
임상이비인후과
2015 .06
-
Long-term outcomes after salvage radiotherapy for postoperative locoregionally recurrent non-small-cell lung cancer
Radiation oncology journal : ROJ
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0