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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 111 - 115 (5page)
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초록· 키워드
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Purpose: Following the introduction of a multimodal approach to diagnosis and treatment, the prognosis of rhabdomyosarcoma (RMS) has markedly improved over the last three decades. However, there are few data on treatment outcomes in Korean patients.
Materials and Methods: We performed a retrospective analysis of 77 patients with RMS diagnosed and treated at Seoul National University Children's Hospital between 1986 and 2005.
Results: The overall 5-year survival and event-free survival rates for all patients were 77% and 59%, respectively. The Intergroup Rhabdomyosarcoma Study clinical grouping and initial response to treatment (20-week response) were important prognostic factors.
Conclusions: The outcome of childhood RMS was closely associated with the initial staging and the initial response to treatment. Modulating therapies according to initial responses and risk factors is critical, and new treatment strategies for high-risk patients are needed.
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참고문헌 (22)
참고문헌 신청
Bersani F. / 2008 / Bortezomib-mediated proteasome inhibition as a potential strategy for the treatment of rhabdomyosarcoma / Eur J Cancer 44 : 876 ~ 84
Blay JY / 2000 / High-dose chemotherapy with autologous hematopoietic stem-cell transplantation for advanced soft tissue sarcoma in adults / J Clin Oncol 18 : 3643 ~ 50
Burke M. / 2007 / Assessment of response to induction therapy and its influence on 5-year failure-free survival in group III rhabdomyosarcoma: the Intergroup Rhabdomyosarcom
Carli M. / 1999 / High-dose melphalan with autologous stemcell rescue in metastatic rhabdomyosarcoma / J Clin Oncol 17 : 2796 ~ 803
Carli M. / 2004 / European intergroup studies (MMT4-89 and MMT4-91) on childhood metastatic rhabdomyosarcoma: final results and analysis of prognostic factors / J Clin Oncol
Blay JY / 2000 / High-dose chemotherapy with autologous hematopoietic stem-cell transplantation for advanced soft tissue sarcoma in adults / J Clin Oncol 18 : 3643 ~ 50
Burke M. / 2007 / Assessment of response to induction therapy and its influence on 5-year failure-free survival in group III rhabdomyosarcoma: the Intergroup Rhabdomyosarcom
Carli M. / 1999 / High-dose melphalan with autologous stemcell rescue in metastatic rhabdomyosarcoma / J Clin Oncol 17 : 2796 ~ 803
Carli M. / 2004 / European intergroup studies (MMT4-89 and MMT4-91) on childhood metastatic rhabdomyosarcoma: final results and analysis of prognostic factors / J Clin Oncol
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