지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 949 - 953 (5page)
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초록· 키워드
오류제보하기
Oxaliplatin is a third-generation platinum derivative used for metastatic or advancedcolorectal cancer treatment. Although myelosuppression is the most common causeof oxaliplatin-induced thrombocytopenia, rare cases of oxaliplatin-induced immunemediatedthrombocytopenia are reported. We report a case of a 57-year-old womanwith colon cancer who developed gum bleeding and petechiae after oxaliplatininfusion. Laboratory tests revealed grade 4 thrombocytopenia and grade 4 neutropenia.
She recovered from the thrombocytopenia and accompanying neutropenia within4 days with no recurrence following discontinuation of oxaliplatin. Physicians need tobe aware of the risk of severe acute thrombocytopenia following oxaliplatinadministration.
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Andre T / 2004 / Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer / N Engl J Med 350 : 2343 ~ 2351
Bautista MA / 2010 / Hypersensitivity reaction and acute immune-mediated thrombocytopenia from oxaliplatin : two case reports and a review of the literature / J Hematol Oncol
Colucci G / 2005 / Phase III randomized trial of FOLFIRI versus FOLFOX4in the treatment of advanced colorectal cancer : a multicenter study of the Gruppo Oncologico Dell'Ital
Curtis BR / 2006 / Immune-mediated thrombocytopenia resulting from sensitivity to oxaliplatin / Am J Hematol 81 : 193 ~ 198
Fontao-Wendel R / 2010 / Immune-mediated pancytopenia induced by oxaliplatin : a case report / Transfusion 50 : 1453 ~ 1459
Bautista MA / 2010 / Hypersensitivity reaction and acute immune-mediated thrombocytopenia from oxaliplatin : two case reports and a review of the literature / J Hematol Oncol
Colucci G / 2005 / Phase III randomized trial of FOLFIRI versus FOLFOX4in the treatment of advanced colorectal cancer : a multicenter study of the Gruppo Oncologico Dell'Ital
Curtis BR / 2006 / Immune-mediated thrombocytopenia resulting from sensitivity to oxaliplatin / Am J Hematol 81 : 193 ~ 198
Fontao-Wendel R / 2010 / Immune-mediated pancytopenia induced by oxaliplatin : a case report / Transfusion 50 : 1453 ~ 1459
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