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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 774 - 780 (7page)
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초록· 키워드
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Purpose This study investigated setup error and effectiveness of weekly image-guided radiotherapy(IGRT) of TomoDirect for early breast cancer.
Materials and MethodsOne hundred and fifty-one breasts of 147 consecutive patients who underwent breastconserving surgery followed by whole breast irradiation using TomoDirect in 2012 and 2013were evaluated. All patients received weekly IGRT. The weekly setup errors from simulationto each treatment in reference to chest wall and surgical clips were measured. Random,systemic, and 3-dimensional setup errors were assessed. Extensive setup error wasdefined as 5 mm above the margin in any directions.
ResultsAll mean errors were within 3 mm of all directions. The mean angle of gantry shifts was0.6°. The mean value of absolute 3-dimensional setup error was 4.67 mm. In multivariateanalysis, breast size (odds ratio, 2.82; 95% confidence interval, 1.00 to 7.90) was a significantfactor for extensive error. The largest significant deviation of setup error was observedin the first week of radiotherapy (p < 0.001) and the deviations gradually decreased withtime. The deviation of setup error was 5.68 mm in the first week and within 5 mm after thesecond week.
ConclusionIn this study, there was a significant association between breast size and significant setuperror in breast cancer patients who received TomoDirect. The largest deviation occurred inthe first week of treatment. Therefore, patients with large breasts should be closely observedon every fraction and fastidious attention is required in the first fraction of IGRT.
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참고문헌 (22)
참고문헌 신청
이종훈 / 2010 / Predictors of Axillary Lymph Node Metastases (ALNM) in a Korean Population with T1-2 Breast Carcinoma: Triple Negative Breast Cancer has a High Incidence of ALNM Irrespective of the Tumor Size / Cancer Research and Treatment 42(1):30~36
Richter A / 2009 / Effect of breathing motion in radiotherapy of breast cancer : 4D dose calculation and motion tracking via EPID / Strahlenther Onkol 185:425~430
Bert C / 2006 / Clinical experience with a 3D surface patient setup system for alignment of partial-breast irradiation patients / Int J Radiat Oncol Biol Phys 64:1265~1274
/ / Brassiere measurement / Wikipedia
/ 2006 / NSABP B-39, RTOG 0413: A randomized phase III study of conventional whole breast irradiation versus partial breast irradiation for women with stage 0, I, or II brea
Richter A / 2009 / Effect of breathing motion in radiotherapy of breast cancer : 4D dose calculation and motion tracking via EPID / Strahlenther Onkol 185:425~430
Bert C / 2006 / Clinical experience with a 3D surface patient setup system for alignment of partial-breast irradiation patients / Int J Radiat Oncol Biol Phys 64:1265~1274
/ / Brassiere measurement / Wikipedia
/ 2006 / NSABP B-39, RTOG 0413: A randomized phase III study of conventional whole breast irradiation versus partial breast irradiation for women with stage 0, I, or II brea
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