지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives: Autonomic nerve system dysfunction has been reported in patients following traumatic brain injury (TBI). However, studies providing direct evidence of a link between the two have been scarce. The purpose of the present study was to evaluate cardiac autonomic modulation in post-acute ambulatory outpatients with TBI using an analysis of heart rate variability (HRV).
Methods: Twenty-one patients with TBI and 21 age- and gender- matched normal controls were evaluated. The HRV assessments were performed using conventional time and frequency domain analyses as well as non-linear complexity analysis.
Results: In the patient group, standard deviation values of the RR intervals (SDNN), the square root of the mean squared differences of successive normal sinus intervals (RMSSD), total successive RR interval difference (TSRD), and the very low frequency (VLF) power spectral parameter were significantly lower than in the control group. The patients with moderate severity of TBI exhibited a significantly lower value of VLF than those with mild severity. The severity of anxiety symptoms had a tendency to be correlated with the mean heart rate and the ratio of low-to-high frequency spectral power.
Conclusion: The results of the present study provide evidence that TBI is associated with reduced HRV, suggesting the critical involvement of central autonomic structures in the pathogenesis of TBI. The HRV measures may serve as an index for monitoring aspects of autonomic function in patients with TBI.
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Agelink MW / 2001 / Effects of newer atypical antipsychotics on autonomic neurocardiac function: a comparison between amisulpride, olanzapine, sertindole, and clozapine / J
Annegers JF / 1980 / The incidence, causes, and secular trends of head trauma in Olmsted County, Minnesota, 1935-1974 / Neur
Baguley IJ / 2008 / Autonomic complications following central nervous system injury / Semin Neurol 28 : 716 ~ 725
Baguley IJ / 2009 / Diagnosing dysautonomia after acute traumatic brain injury: evidence for overresponsiveness to afferent stimuli / Arch Phys Med Rehabil 90 : 580 ~ 586
Baillard C / 2002 / Brain death assessment using instant spectral analysis of heart rate variability / Crit Care Med 30 : 306 ~ 310
Annegers JF / 1980 / The incidence, causes, and secular trends of head trauma in Olmsted County, Minnesota, 1935-1974 / Neur
Baguley IJ / 2008 / Autonomic complications following central nervous system injury / Semin Neurol 28 : 716 ~ 725
Baguley IJ / 2009 / Diagnosing dysautonomia after acute traumatic brain injury: evidence for overresponsiveness to afferent stimuli / Arch Phys Med Rehabil 90 : 580 ~ 586
Baillard C / 2002 / Brain death assessment using instant spectral analysis of heart rate variability / Crit Care Med 30 : 306 ~ 310
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