지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objectives The aim of this study was to investigate associations between obesity indices and cognitive functions using data from individuals older than 65 years in South Korea.
Methods A total of 151 Koreans older than 65 years participated in this study voluntarily. Obesity was determined using body mass index (BMI) and waist-hip ratio (WHR). Cognitive function was evaluated using the Korean version of the Mini-Mental State Examination (MMSE-K). The participants were divided into four groups according to BMI : underweight (BMI<18.5), normal (18.5≤BMI<23.0), overweight (23.0≤BMI<25.0), and obesity (BMI≥25.0), and two groups according to WHR : normal (WHR<18.5) and abdominal obesity (WHR≥0.8). Baseline characteristics were compared among different BMI or WHR subgroups.
Results Older age and smoking habits showed an association with poor cognitive function.
Among different BMI groups, the overweight group had the highest scores of MMSE-K ; the item scores for time and place orientation (4.48±0.770 and 4.80±0.500) and attention/calculation (4.00±1.258) as well as total score (25.88±2.877). Overweight in BMI showed an association with better cognitive function (ORadjusted=0.098, 95% confidence interval=0.017-0.577).
Conclusion In this study, the overweight group measured by BMI showed better cognitive function than other groups. Overweight in elderly might be acceptable in order to maintain cognitive performance. Further investigation regarding the underlying mechanism explaining the relationship between cognitive function and body weight will be needed.
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참고문헌 (30)
참고문헌 신청
Anstey KJ / 2011 / Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies / Obes Rev 12:426~437
Bleecker ML / 1988 / Age-specific norms for the Mini-Mental State Exam / Neurology 38:1565~1568
Brandt J / 1988 / Differential cognitive impairment in Alzheimer’s disease and Huntington’s disease / Ann Neurol 23:555~561
Kang YW / 1997 / A validity study on the Korean Mini- Mental State Examination (K-MMSE) in dementia patients / J Korean Neurol Assoc 15:300~308
Barrett-Connor E / 1996 / Weight loss precedes dementia in community-dwelling older adults / J Am Geriatr Soc 44 : 1147 ~ 1152
Bleecker ML / 1988 / Age-specific norms for the Mini-Mental State Exam / Neurology 38:1565~1568
Brandt J / 1988 / Differential cognitive impairment in Alzheimer’s disease and Huntington’s disease / Ann Neurol 23:555~561
Kang YW / 1997 / A validity study on the Korean Mini- Mental State Examination (K-MMSE) in dementia patients / J Korean Neurol Assoc 15:300~308
Barrett-Connor E / 1996 / Weight loss precedes dementia in community-dwelling older adults / J Am Geriatr Soc 44 : 1147 ~ 1152
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