지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objectives Lack of insight has been regarded as the key feature of schizophrenia since the era of Kraepelin. The relationship between insight and psychopathology has been known to be statistically modest and non-linear. The aim of this study was to investigate psychopathological factors influencing insight achievement during treatment of acute psychotic episodes in schizophrenia, using the Korean version of the Scale to Assess Unawareness of Mental Disorder (SUMD-K) and the Positive and Negative Syndrome Scale (PANSS).
Methods Information on demographic characteristics, SUMD-K, and PANSS were collected from the medical records of patients who were admitted to the psychiatric ward of Dongguk University International Hospital from March 1, 2009 to February 28 and were diagnosed as schizophrenia by the DSM-IV TR 2010. A total of 29 patients met the inclusion criteria. The scores of total and sub-items of SUMD-K for both current and past illnesses were assessed at five weeks after hospitalization and the scores of total and five factors of PANSS were assessed on hospitalization and at five weeks after hospitalization, respectively, and the changes in score between two time points were calculated. Statistical analysis of the relationships between the various items of the SUMD-K and the clinical characteristics, the total and sub-scores of PANSS was performed using the Pearson correlation test and multiple regression analysis with stepwise variable selection.
Results Total score and five factor scores of PANSS for hospitalization and PANSS changes did not show statistical correlation with SUMD-K. The total score of general items and awareness of mental disorder of SUMD-K at five weeks after hospitalization showed significant associations with duration of education, depressed and cognitive factors for current illness of PANSS at five weeks after hospitalization, respectively. In addition, depressed factor and cognitive factor of PANSS showed a significant association with awareness of social consequences and awareness of the achieved affect of medication, respectively.
Conclusion During treatment of acute psychotic episodes in patients with schizophrenia, various domains of psychopathology were differentially correlated with insight, which implied the multidimensional construct on a continuum. Conduct of further studies of neurobiological approaches underlying factors showing correlation with insight is needed.
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참고문헌 (28)
참고문헌 신청
Aleman A / 2006 / Insight in psychosis and neuropsychological function: meta-analysis / Br J Psychiatry 189 : 204 ~ 212
Amador XF / 1993 / Assessment of insight in psychosis / Am J Psychiatry 150 : 873 ~ 879
Beck AT / 2004 / A new instrument for measuring insight: the Beck Cognitive Insight Scale / Schizophr Res 68 : 319 ~ 329
Brent BK / 2011 / Insight into illness in patients and caregivers during early psychosis: a pilot study / Schizophr Res 127 : 100 ~ 106
Carpenter WT Jr / 1973 / Flexible system for the diagnosis of schizophrenia: report from the WHO International Pilot Study of Schizophrenia / Science 182 : 1275 ~ 1278
Amador XF / 1993 / Assessment of insight in psychosis / Am J Psychiatry 150 : 873 ~ 879
Beck AT / 2004 / A new instrument for measuring insight: the Beck Cognitive Insight Scale / Schizophr Res 68 : 319 ~ 329
Brent BK / 2011 / Insight into illness in patients and caregivers during early psychosis: a pilot study / Schizophr Res 127 : 100 ~ 106
Carpenter WT Jr / 1973 / Flexible system for the diagnosis of schizophrenia: report from the WHO International Pilot Study of Schizophrenia / Science 182 : 1275 ~ 1278
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