지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 29 - 34 (6page)
이용수
초록· 키워드
오류제보하기
Background and Purpose Cognitive and cerebrovascular diseases are common in the elderly, but differences in the plasma levels and associations of plasma biomarkers in these diseases remain elusive. Methods The present study investigated differences in plasma fatty acids [eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)], adiponectin, reptin, plasma markers of inflammation [high-sensitivity C-reactive protein (hsCRP) and serum amyloid A (serum AA)], and plasma lipids [high-density lipoprotein and low-density lipoprotein (LDL)] in patients with Alzheimer’s disease (AD) (n=266), mild cognitive impairment (MCI) (n=44), vascular dementia (VaD) (n=33), and ischemic stroke (IS) (n=200) in comparison to normal controls (n=130). Results The serological data showed that lower EPA and DHA levels and higher reptin and LDL levels were associated with AD and IS, the reptin/adiponectin ratio was strongly associated with IS, the hsCRP level was more strongly associated with VaD and IS, and the serum AA level was associated with all three cognitive diseases and IS. Conclusions This is the first report of differences in the expression levels of plasma biomarkers and peripheral arterial tonometry among AD, MCI, VaD, and IS patients and normal controls. These different associations indicate that diverse pathological mechanisms underlie these diseases
목차
등록된 정보가 없습니다.
참고문헌 (1)
참고문헌 신청
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
알츠하이머병에서 혈장 크레아틴과 염증반응, 인지기능과의 연관성
노인정신의학
2021 .10
-
Clinical Application of Plasma Neurofilament Light Chain in a Memory Clinic: A Pilot Study
Dementia and Neurocognitive Disorders(대한치매학회지)
2022 .04
-
Baseline Clinical and Biomarker Characteristics of Biobank Innovations for Chronic Cerebrovascular Disease With Alzheimer’s Disease Study: BICWALZS
PSYCHIATRY INVESTIGATION
2022 .02
-
The Association of Blood-Based Inflammatory Factors IL-1β, TGF-β and CRP with Cognitive Function in Alzheimer’s Disease and Mild Cognitive Impairment
PSYCHIATRY INVESTIGATION
2021 .01
-
Associations of Serum Isoleucine with Mild Cognitive Impairment and Alzheimer’s Disease
Annals of geriatric medicine and research
2024 .09
-
The Correlation Study between Plasma Aβ Proteins and Cerebrospinal Fluid Alzheimer’s Disease Biomarkers
Dementia and Neurocognitive Disorders(대한치매학회지)
2016 .12
-
Bias-generating factors in biofluid amyloid-β measurements for Alzheimer’s disease diagnosis
Biomedical Engineering Letters (BMEL)
2021 .12
-
알츠하이머병과 경도인지장애에서의 혈장 섬유소원과 C 반응 단백의 농도
노인정신의학
2019 .01
-
Alzheimer's Disease Diagnosis Using Misfolding Proteins in Blood
Dementia and Neurocognitive Disorders(대한치매학회지)
2020 .01
-
Predicting the Progression of Mild Cognitive Impairment to Alzheimer’s Dementia Using Recurrent Neural Networks With a Series of Neuropsychological Tests
Journal of Clinical Neurology
2024 .09
-
Reference Intervals for Plasma Amyloid β in Korean Adults Without Cognitive Impairment
Annals of Laboratory Medicine
2016 .01
-
Panax Ginseng in the treatment of Alzheimer’s disease and vascular dementia
Journal of Ginseng Research
2023 .07
-
혈장 염증 시토카인과 치매, 경도인지장애 진단의 연관성
생물치료정신의학
2019 .02
-
경도인지장애 환자들을 대상으로 한인지중재치료의 임상 실제
신경정신의학
2018 .01
-
경도인지장애의 아형분류와 치료
임상노인의학회지
2021 .12
-
Structural MRI and Amyloid PET Imaging for Prediction of Conversion to Alzheimer’s Disease in Patients with Mild Cognitive Impairment: A Meta-Analysis
PSYCHIATRY INVESTIGATION
2017 .01
-
Incidence and Risk Factors for Dementia in Type 2 Diabetes Mellitus: A Nationwide Population-Based Study in Korea
Diabetes and Metabolism Journal
2020 .01
-
Cerebrospinal Biomarker Cut-off Methods Defined Only by Alzheimer’s Disease Predict More Precisely Conversions of Mild Cognitive Impairment
Dementia and Neurocognitive Disorders(대한치매학회지)
2017 .01
-
Low Plasma Proportion of Omega 3-Polyunsaturated Fatty Acids Predicts Poor Outcome in Acute Non-Cardiogenic Ischemic Stroke Patients
대한뇌졸중학회지
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0