지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives：This study aimed to test the possible association between Glutathione S-Transferase M1 gene (GSTM1) variants
and schizophrenia.
Methods：One hundred and eleven inpatients with schizophrenia and 130 healthy controls were recruited. Genotyping was
performed by polymerase chain reaction-based method.
Results：The GSTM1 null genotype was significantly more frequent in patients with schizophrenia than in controls (p=0.014,
odd ratio=1.93, 95% confidence interval=1.115-3.351), while GSTM1 genotype variants were not associated with either
tardive dyskinesia (TD) or total Abnormal Involuntary Movement Scale (AIMS) scores.
Conclusion：The present study suggests that the GSTM1 polymorphism may confer susceptibility to the development of
schizophrenia but not to TD, at least in Korean population. (J Korean Neuropsychiatr Assoc 2004;43(5):519-523)
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
/ 1976 / ECDEUassessment manual for psychopharmacology : 534 ~ 537
/ 1982 / Research diagnoses for tardive dyskinesia 39 : 486 ~ 487
/ 1987 / Haplotype relative risks:an easy reliable way toconstruct a proper control sample for risk calculations 51 : 227 ~ 233
/ 1989 / Red cell enzyme and serum protein polymorphisms in South Korea 39 : 263 ~ 270
/ 1990 / Increased Indices of free radicalactivity in the cerebrospinal fluid of patients with tardive dyskinesia 28 : 535 ~ 539
/ 1982 / Research diagnoses for tardive dyskinesia 39 : 486 ~ 487
/ 1987 / Haplotype relative risks:an easy reliable way toconstruct a proper control sample for risk calculations 51 : 227 ~ 233
/ 1989 / Red cell enzyme and serum protein polymorphisms in South Korea 39 : 263 ~ 270
/ 1990 / Increased Indices of free radicalactivity in the cerebrospinal fluid of patients with tardive dyskinesia 28 : 535 ~ 539
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