지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 139 - 145 (7page)
이용수
초록· 키워드
오류제보하기
Background and Purpose The most important treatment for subcortical vascular dementia
(SVaD) is controlling the blood pressure (BP). However, the few studies that have investigated the
relationships between diurnal BP rhythm and subcortical ischemic vascular cognitive impairment
have produced inconclusive results. In the study presented here, the 24-hour BP values of three
groups of subjects-patients with subcortical vascular mild cognitive impairment (SvMCI), patients
with SVaD, and normal controls-were compared using working criteria and 24-hour ambulatory
BP (ABP) monitoring.
Methods The subjects (42 patients with SVaD, 37 patients with SvMCI, and 30 controls) were
selected according to the study’s inclusion/exclusion criteria. All subjects underwent brain
magnetic resonance (MR) imaging and MR angiography, detailed neuropsychological testing,
and 24-hour ABP monitoring.
Results The prevalence of nondippers differed markedly between the control group and both
the SVaD and SvMCI groups. Loss of nocturnal dipping was significantly associated with SVaD
[odds ratio (OR), 4.827; 95% confidence interval (CI), 1.07-12.05].
Conclusions It was found that SVaD is associated with loss of nocturnal BP dipping combined
with increased pulse pressure and systolic BP (SBP) variability. Correction of these factors
could therefore be important in the prevention of SVaD, independent of measures used to
reduce BP.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Birns J / 2005 / Blood pressure reduction for vascular risk: is there a price to be paid? / Stroke 36 : 1308 ~ 1313
Bowler JV / 2005 / Vascular cognitive impairment / J Neurol Neurosurg Psychiatry 7 (5) : v35 ~ v44
Dufouil C / 2001 / Longitudinal study of blood pressure and white matter hyperintensities: the EVA MRI Cohort / Neurology 56 : 921 ~ 926
Guo Z / 1997 / Blood pressure and performance on the Mini-Mental State Examination in the very old. Cross-sectional and longitudinal data from the Kungsholmen Project / Am J
Hachinski VC / 1975 / Cerebral blood flow in dementia / Arch Neurol 32 : 632 ~ 637
Bowler JV / 2005 / Vascular cognitive impairment / J Neurol Neurosurg Psychiatry 7 (5) : v35 ~ v44
Dufouil C / 2001 / Longitudinal study of blood pressure and white matter hyperintensities: the EVA MRI Cohort / Neurology 56 : 921 ~ 926
Guo Z / 1997 / Blood pressure and performance on the Mini-Mental State Examination in the very old. Cross-sectional and longitudinal data from the Kungsholmen Project / Am J
Hachinski VC / 1975 / Cerebral blood flow in dementia / Arch Neurol 32 : 632 ~ 637
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