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- 학술저널
- 저자정보
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- 2008.1
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A significant minority of patients with focal epilepsy are candidates for resective epilepsy surgery. Structural and
functional neuroimaging plays an important role in the presurgical evaluation of theses patients. The most frequent
etiologies of pharmacoresistant epilepsy in the adult population are mesial temporal sclerosis, malformations of
cortical development, cavernous angiomas, and low-grade neoplasms. High-resolution multiplanar magnetic
resonance imaging (MRI) with sequences providing T1 and T2 contrast is the initial imaging study of choice to
detect these epileptogenic lesions. The epilepsy MRI protocol can be individually tailored when considering the
patient’s clinical and electrophysiological data. Metabolic imaging techniques such as positron emission tomography
(PET) and single photon emission tomography (SPECT) visualize metabolic alterations of the brain in the
ictal and interictal states. These techniques may have localizing value in patients with a normal MRI scan.
Functional MRI is helpful in non-invasively identifying areas of eloquent cortex.
Developments in imaging technology and digital postprocessing may increase the yield for imaging studies to
detect the epileptogenic lesion and to characterize its connectivity within the epileptic brain.
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참고문헌 (24)
참고문헌 신청
/ 1997 / Recommendations for neuroimaging of patients with epilepsy. commission on neuroimaging of the international league against epilepsy / Epilepsia 38 : 1255 ~ 1256
/ 1998 / Guidelines for neuroimaging evaluation of patients with uncontrolled epilepsy considered for surgery. commission on neuroimaging of the international league against
ACEP Clinical Policies Committee / 2004 / Clinical Policies Subcommittee on Seizures. Clinical policy: Critical issues in the evaluation and management of adult patients pre
Beaumont A / 2000 / The pathogenesis of tumour associated epilepsy / Acta Neurochir (Wien) 142 : 1 ~ 15
Berkovic SF / 1995 / Preoperative MRI predicts outcome of temporal lobectomy: An actuarial analysis / Neurology 45 : 1358 ~ 1363
/ 1998 / Guidelines for neuroimaging evaluation of patients with uncontrolled epilepsy considered for surgery. commission on neuroimaging of the international league against
ACEP Clinical Policies Committee / 2004 / Clinical Policies Subcommittee on Seizures. Clinical policy: Critical issues in the evaluation and management of adult patients pre
Beaumont A / 2000 / The pathogenesis of tumour associated epilepsy / Acta Neurochir (Wien) 142 : 1 ~ 15
Berkovic SF / 1995 / Preoperative MRI predicts outcome of temporal lobectomy: An actuarial analysis / Neurology 45 : 1358 ~ 1363
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