지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제3권 제6호
- 발행연도
- 2015.1
- 수록면
- 446 - 448 (3page)
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초록· 키워드
오류제보하기
Stevens-Johnson syndrome (SJS) manifests with severe cutaneous reactions, most commonly triggered by medications, which are characterized by fever and mucocutaneous lesions leading to necrosis and sloughing of the epidermis. To our knowledge, pravastatin-induced SJS has not yet been reported. Here, we describe a case of SJS due to pravastatin, which was diagnosed by a patch test. A 70-year-old woman presented with maculopapular skin rashes, which developed 2 weeks after medication of bisoprolol, amlodipine, pravastatin, spironolactone, and indobufene for cardiac problems. Various bullous-erosive mucocutaneous lesions occupied less than 10% of the total body surface area. Painful oropharyngeal mucous membrane lesions were observed. The vermilion border of the lips became denuded and developed serosanguinous crusts. With the drug withdrawal and the use of systemic corticosteroids, her manifestations resolved. Drug patch tests with bisoprolol, amlodipine, pravastatin, spironolactone, and indobufene were performed, resulting in a positive reaction to pravastatin, but not to the other drugs. To the best of our knowledge, this is the first case of pravastatin-induced SJS.
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참고문헌 (9)
참고문헌 신청
Adams AE / 2010 / Statins and"chameleon-like"cutaneous eruptions : simvastatin-induced acral cutaneous vesiculobullous and pustular eruption in a 70-year-old man / J Cutan Me
Fregert S / 1981 / Manual of contact dermatitis / Munksgaard Publishers
Gressier L / 2009 / Atorvastatin-induced drug reaction with eosinophilia and systemic symptoms(DRESS) / Ann Dermatol Venereol 136 : 50 ~ 53
Hydzik P / 2011 / Side effects of the HMG-CoA reductase inhibitors (statins). Lupus erythematosus induced by Atorvastatin therapy / Przegl Lek 68 : 495 ~ 498
Peters AT / 2009 / Patterson's allergic diseases : 232 ~ 235
Fregert S / 1981 / Manual of contact dermatitis / Munksgaard Publishers
Gressier L / 2009 / Atorvastatin-induced drug reaction with eosinophilia and systemic symptoms(DRESS) / Ann Dermatol Venereol 136 : 50 ~ 53
Hydzik P / 2011 / Side effects of the HMG-CoA reductase inhibitors (statins). Lupus erythematosus induced by Atorvastatin therapy / Przegl Lek 68 : 495 ~ 498
Peters AT / 2009 / Patterson's allergic diseases : 232 ~ 235
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