지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제18권 제3호
- 발행연도
- 2008.1
- 수록면
- 202 - 207 (6page)
이용수
초록· 키워드
오류제보하기
Exacerbations of asthma is major causes of morbidity, mortality, and health-care costs. Over the decade, studies using new molecular diagnostic techniques have established that respiratory viruses are a major cause of exacerbations of asthma. The most prevalent viruses detected during exacerbations are the rhinovirus. Despite the burden of disease associated with exacerbations, little is known about the mechanisms of virus-induced exacerbations of airway diseases. Exacerbations are associated with increased airway inflammation in patients with asthma, but many questions remain unanswered regarding the key inflammatory cells and mediators involved. Identifying the key inflammatory mediators involved in exacerbations holds the promise of developing diagnostic and prognostic markers of exacerbation. The purpose of this review is to summarize the recent change in our understanding of the clinical manifestations of rhinovirus infection than occurred as a result of the improved diagnostic sensitivity provided by the multiplex-polymerase chain reaction (PCR) assays and serotypes.
목차
등록된 정보가 없습니다.
참고문헌 (32)
참고문헌 신청
Brownlee JW / 2008 / New developments in the epidemiology and clinical spectrum of rhinovirus infections / Curr Opin Pediatr 20:67~71
Cheuk DK / 2007 / Rhinovirus infection in hospitalized children in Hong Kong: a prospective study / Pediatr Infect Dis J 26:995~1000
Edwards MR / 2006 / Combination therapy: synergistic suppression of virus-induced chemokines in airway epithelial cells / Am J Respir Cell Mol Biol 34:616~624
Jartti T / 2007 / Atopic characteristics of wheezing children and responses to prednisolone / Pediatr Pulmonol 42:1125~1133
Bisgaard H / 2005 / Montelukast reduces asthma exacerbations in 2- to 5-year-old children with intermittent asthma / Am J Respir Crit Care Med 171:315~322
Cheuk DK / 2007 / Rhinovirus infection in hospitalized children in Hong Kong: a prospective study / Pediatr Infect Dis J 26:995~1000
Edwards MR / 2006 / Combination therapy: synergistic suppression of virus-induced chemokines in airway epithelial cells / Am J Respir Cell Mol Biol 34:616~624
Jartti T / 2007 / Atopic characteristics of wheezing children and responses to prednisolone / Pediatr Pulmonol 42:1125~1133
Bisgaard H / 2005 / Montelukast reduces asthma exacerbations in 2- to 5-year-old children with intermittent asthma / Am J Respir Crit Care Med 171:315~322
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