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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제51권 제2호
- 발행연도
- 2017.1
- 수록면
- 176 - 179 (4page)
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Breast cancers that present with mucin include mucinous carcinoma and carcinoma with signet ring cell differentiation. The former shows extracellular mucin and the latter shows abundant intracellular mucin. Here, we report a case of breast cancer showing both extracellular mucin and extensive signet ring cell differentiation due to abundant intracellular mucin. Unlike mucinous carcinoma, this case had the features of high-grade nuclear pleomorphism, high mitotic index, estrogen receptor negativity, progesterone receptor negativity, human epidermal growth factor receptor-2 positivity, and ductal type with positivity for E-cadherin. In a case with signet ring cell differentiation, differential diagnosis with metastatic signet ring cell carcinoma of the stomach and colon is essential. In this case, the presence of accompanied ductal carcinoma in situ component and mammaglobin and gross cystic disease fluid protein-15 positivity were findings that suggested the breast as the origin.
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등록된 정보가 없습니다.
참고문헌 (12)
참고문헌 신청
Barkley CR / 2008 / Mucinous breast carcinoma: a large contemporary series / Am J Surg 196 : 549 ~ 551
Bartosch C / 2015 / Morphological features and mucin expression profile of breast carcinomas with signet-ring cell differentiation / Pathol Res Pract 211 : 588 ~ 595
Chu PG / 2004 / Immunohistochemical characterization of signet-ring cell carcinomas of the stomach, breast, and colon / Am J Clin Pathol 121 : 884 ~ 892
Coady AT / 1989 / Mucinous carcinoma of the breast: further characterization of its three subtypes / Histopathology 15 : 617 ~ 626
Frost AR / 1995 / The significance of signet ring cells in infiltrating lobular carcinoma of the breast / Arch Pathol Lab Med 119 : 64 ~ 68
Bartosch C / 2015 / Morphological features and mucin expression profile of breast carcinomas with signet-ring cell differentiation / Pathol Res Pract 211 : 588 ~ 595
Chu PG / 2004 / Immunohistochemical characterization of signet-ring cell carcinomas of the stomach, breast, and colon / Am J Clin Pathol 121 : 884 ~ 892
Coady AT / 1989 / Mucinous carcinoma of the breast: further characterization of its three subtypes / Histopathology 15 : 617 ~ 626
Frost AR / 1995 / The significance of signet ring cells in infiltrating lobular carcinoma of the breast / Arch Pathol Lab Med 119 : 64 ~ 68
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