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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제43권 제4호
- 발행연도
- 2009.1
- 수록면
- 351 - 354 (4page)
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We report a case of perigastric histiocytic sarcoma (HS) involving the lesser omental sac in a 30-year-old man. HS is an exceedingly rare malignancy of mature tissue histiocyte. The tumor was a multi-lobulated, bulging enhancing mass in the lesser omentum with metastasis to lymph nodes and liver. The tumor consisted of diffuse non-cohesive proliferation of pleomorphic large
oval to round neoplastic cells with giant cells showing vesicular chromatin and ample eosinophilic cytoplasm. In some areas, the tumor cells showed spindling with elongation of the nuclei and cellular shapes. Many of the tumor cells, especially giant forms contained phagocytosed lymphocytes.
Immunohistochemical analysis of the tumor cells showed expression of leukocyte common antigen, CD68, lysozyme, vimentin, CD4, and CD163. Ki-67 index was 50-60%. After the operation, he was treated with chemotherapy, but the response was poor.
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참고문헌 (7)
참고문헌 신청
Copie-Bergman C / 1998 / True histiocytic lymphoma: a morphologic, immunohistochemical, and molecular genetic study of 13 cases / Am J Surg Pathol 22 : 1386 ~ 1392
Hornick JL / 2004 / Extranodal histiocytic sarcoma:clinicopathologic analysis of 14 cases of a rare epithelioid malignancy / Am J Surg Pathol 28 : 1133 ~ 1144
Pileri SA / 2002 / Tumours of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based o
Vos JA / 2005 / Histiocytic sarcoma: a study of five cases including the histiocyte marker CD163 / Mod Pathol 18 : 693 ~ 704
Weiss LM / 2001 / Histiocytic sarcoma. in: World Health Organization classification of tumours. Pathology and genetics of tumours of haematopoietic and lymphoid tissues / IARC R-ess : 27
Hornick JL / 2004 / Extranodal histiocytic sarcoma:clinicopathologic analysis of 14 cases of a rare epithelioid malignancy / Am J Surg Pathol 28 : 1133 ~ 1144
Pileri SA / 2002 / Tumours of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based o
Vos JA / 2005 / Histiocytic sarcoma: a study of five cases including the histiocyte marker CD163 / Mod Pathol 18 : 693 ~ 704
Weiss LM / 2001 / Histiocytic sarcoma. in: World Health Organization classification of tumours. Pathology and genetics of tumours of haematopoietic and lymphoid tissues / IARC R-ess : 27
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