지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 322 - 328 (7page)
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초록· 키워드
오류제보하기
Histiocytic sarcoma is a type of lymphoma that rarely involves the central nervoussystem (CNS). Its rarity can easily lead to a misdiagnosis. We describe a patient withprimary CNS histocytic sarcoma involving the cerebral hemisphere and spinal cord,who had been initially misdiagnosed as demyelinating disease. Two biopsies werenecessary before a correct diagnosis was made. A histologic examination showedbizarre shaped histiocytes with larger nuclei and nuclear atypia. The cells werepositive for CD68, CD163, and S-100 protein. As a resection was not feasible due tomultifocality, he was treated with highdose methotrexate, but showed no response.
As a result, he was switched to high dose cytarabine; but again, showed no response.
The patient died 2 months from the start of chemotherapy and 8 months from theonset of symptoms. Since few patients with this condition have been described andhistopathology is difficult to diagnose, suspicion of the disease is essential.
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등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Almefty RO / 2013 / Primary histiocytic sarcoma of the brain mimicking cerebral abscess / J Neurosurg Pediatr 12 : 251 ~ 257
Bell SL / 2012 / Primary meningeal histiocytic sarcoma : a report of two unusual cases / Neuropathol Appl Neurobiol 38 : 111 ~ 114
Cao M / 2007 / Primary central nervous system histiocytic sarcoma with relapse to mediastinum : a case report and review of the literature / Arch Pathol Lab Med 131 : 301 ~
Cheuk W / 2001 / Primary histiocytic lymphoma of the central nervous system : a neoplasm frequently overshadowed by a prominent inflammatory component / Am J Surg Pathol 25 :
Devic P / 2012 / Histiocytic sarcoma of the central nervous system : a challenging diagnosis / QJM 105 : 77 ~ 79
Bell SL / 2012 / Primary meningeal histiocytic sarcoma : a report of two unusual cases / Neuropathol Appl Neurobiol 38 : 111 ~ 114
Cao M / 2007 / Primary central nervous system histiocytic sarcoma with relapse to mediastinum : a case report and review of the literature / Arch Pathol Lab Med 131 : 301 ~
Cheuk W / 2001 / Primary histiocytic lymphoma of the central nervous system : a neoplasm frequently overshadowed by a prominent inflammatory component / Am J Surg Pathol 25 :
Devic P / 2012 / Histiocytic sarcoma of the central nervous system : a challenging diagnosis / QJM 105 : 77 ~ 79
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