지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제38권 제1호
- 발행연도
- 2004.1
- 수록면
- 23 - 28 (6page)
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초록· 키워드
오류제보하기
Background : This study was performed to examine the significance of the circumferential
resection margin (CRM) involvement by a tumor on the postoperative survival after esophageal
cancer surgery. Methods : Fifty nine resected cases of esophageal cancers were retrospectively
reviewed. The presence of a tumor either at, or within 1 mm of, the CRM was recorded.
By an immunohistochemical study for Ki-67, the Ki-67 differential grades (Ki-67 DG) were
defined according to the differences between the Ki-67 labeling indices of the central and of
peripheral areas of the tumor nearest to the CRM: Ki-67 DG 0 (≤10%) and Ki-67 DG 1 (>10%).
The CRM involvement was correlated with the clinicopathological factors, Ki-67 DG and survival
data. Results : CRM involvement was found in 26 (44.1%) of the 59 cases. There were
significant differences in the cases, both with and without CRM involvement of tumor cells, in
relation to lymph node metastasis, lymphovascular, perineural invasions and tumor stage
(p<0.05). Ten (38.3%) of the 26 with, and 3 (9.1%) of 33 cases without, CRM involvement,
showed Ki-67 DG 1 (p=0.007). The 3-year survivals of patients with and without CRM involvement
were 26.8 and 61.8%, respectively (p=0.003). Conclusions : These results show that
the CRM involvement status may be used as a predictor of survival after esophageal cancer
surgery, and CRM involvement is more an indicator of an advanced disease than of an incomplete
resection.
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
/ 1986 / Local recurrence of rectaladenocarcinoma due to inadequate surgical resection Histopatholog-ical study of lateral tumor spread and surgical excision 11 : 996 ~ 9
/ 1990 / in collaboration with pathologistsin eight countries World HealthOrganization International histological classification of tumors : 11 ~ 8
/ 1992 / Cell cycle dependent expression and sta-bility of the nuclear protein detected by Ki-67 antibody in SHL-60cells 25 : 31 ~ 40
/ 1993 / Signifi-cance of circumferential resection margin involvement after oesopha-gectomy for cancer 80 : 1386 ~ 8
/ 1995 / Prognostic significance ofthe MIB-1 proliferative index for patients with squamous cell carcinomaof the esophagus 76 : 358 ~ 366
/ 1990 / in collaboration with pathologistsin eight countries World HealthOrganization International histological classification of tumors : 11 ~ 8
/ 1992 / Cell cycle dependent expression and sta-bility of the nuclear protein detected by Ki-67 antibody in SHL-60cells 25 : 31 ~ 40
/ 1993 / Signifi-cance of circumferential resection margin involvement after oesopha-gectomy for cancer 80 : 1386 ~ 8
/ 1995 / Prognostic significance ofthe MIB-1 proliferative index for patients with squamous cell carcinomaof the esophagus 76 : 358 ~ 366
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