지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Background/Aims:Diastolic dysfunction may develop in conjunction with or without systolic dysfunction in patients with acute myocardial infarction (AMI). The present study investigated the association between left arterial (LA) volume and major adverse cardiac events (MACE) in 772 patients with AMI.
Methods:The patients were divided into groups according to LA volume index (LAVI) measured using echocardiography according to the American Society of Echocardiography guidelines: LAVI ≥ 40 mL/m2 (Group I: n = 260, 191 males; age, 71.1 ± 10.8 years) and LAVI < 40 mL/m2 (Group II: n = 512, 432 males; age, 62.8 ± 12.7 years). The mean observational period was 314.2 ± 134.6 days.
Results:Group I patients were older than those in Group II. Hypertension (56.8% vs. 46.0%, respectively; p = 0.007) and advanced Killip class (42.6% vs. 21.0%, respectively; p < 0.001) were more frequent in Group I than in Group II. MACE was more prevalent in Group I than in Group II (20.3% vs. 13.7%, respectively; p = 0.037). MACE-free survival rates were higher in Group II than in Group I during clinical follow-up. The multivariate analysis revealed that high LAVI was an independent predictor of mortality (hazard ratio, 3.002; confidedce interval, 1.051-8.569; p = 0.040).
Conclusions:LA volume is an independent predictor of adverse cardiac events in patients with AMI, and the LAVI is useful for AMI risk stratification.
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참고문헌 (19)
참고문헌 신청
Appleton CP / 1993 / Estimation of left ventricular filling pressures using two-dimensional and Doppler echocardiography in adult patients with cardiac disease: additional v
Basnight MA / 1991 / Pulmonary venous flow velocity: relation to hemodynamics, mitral flow velocity and left atrial volume, and ejection fraction / J Am Soc Echocardiogr 4 :
Cerisano G / 2001 / Prognostic implications of restictive left ventricular filling in reperfused anterior acute myocardial infarction / J Am Coll Cardiol 37 : 793 ~ 799
Chen KY / 2009 / Triple versus dual antiplatelet therapy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary interventi
Giannuzzi P / 1996 / Independent and incremental prognostic value of Doppler-derived mitral deceleration time of early filling in both symptomatic and asymptomatic patients
Basnight MA / 1991 / Pulmonary venous flow velocity: relation to hemodynamics, mitral flow velocity and left atrial volume, and ejection fraction / J Am Soc Echocardiogr 4 :
Cerisano G / 2001 / Prognostic implications of restictive left ventricular filling in reperfused anterior acute myocardial infarction / J Am Coll Cardiol 37 : 793 ~ 799
Chen KY / 2009 / Triple versus dual antiplatelet therapy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary interventi
Giannuzzi P / 1996 / Independent and incremental prognostic value of Doppler-derived mitral deceleration time of early filling in both symptomatic and asymptomatic patients
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