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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 38 - 41 (4page)
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Hemophagocytic lymphohistiocytosis (HLH) is a rare but fatal complication after solid organ transplantation. Acquired forms of HLH are described in association with severe sepsis, autoimmune disorders, malignancy, immune-compromised states, infections, and solid organ transplantation. We experienced a case of hemophagocytic lymphohistiocytosis after bilateral lung transplantation. Leukopenia,thrombocytopenia, and hyperbilirubinemia were noted and became aggravated 50 days after transplantation. Diagnosis of HLH was based on clinical and laboratory findings of splenomegaly, cytopenia, elevated ferritin, elevated interleukin-2 receptor, and hemophagocytosis in bone marrow. Other features such as elevated bilirubin, lactate dehydrogenase, and D-dimer which can be present in HLH were also noted. The patient was immediately treated with etoposide and dexamethasone. Despite aggressive therapy, the patient deteriorated and died. Awareness of the diagnostic criteria of HLH after lung transplantation is important for clinicians.
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참고문헌 (6)
참고문헌 신청
Diaz-Guzman E / 2011 / Hemophagocytic lymphohistiocytosis after lung transplant: report of 2 cases and a literature review / Exp Clin Transplant 9 : 217 ~ 222
Henter JI / 2007 / HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis / Pediatr Blood Cancer 48 : 124 ~ 131
Janka GE / 2014 / Hemophagocytic syndromesan update / Blood Rev 28 : 135 ~ 142
Karras A / 2004 / Groupe Cooperatif de transplantation d’lle de France: Hemophagocytic syndrome in renal transplant recipients: report of 17cases and review of literature /
Oto T / 2010 / Hemophagocytic syndrome: a rare but specific complication of lung transplantation / J Thorac Cardiovasc Surg 140 : e58 ~ e59
Henter JI / 2007 / HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis / Pediatr Blood Cancer 48 : 124 ~ 131
Janka GE / 2014 / Hemophagocytic syndromesan update / Blood Rev 28 : 135 ~ 142
Karras A / 2004 / Groupe Cooperatif de transplantation d’lle de France: Hemophagocytic syndrome in renal transplant recipients: report of 17cases and review of literature /
Oto T / 2010 / Hemophagocytic syndrome: a rare but specific complication of lung transplantation / J Thorac Cardiovasc Surg 140 : e58 ~ e59
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