지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 143 - 150 (8page)
이용수
초록· 키워드
오류제보하기
Amino acid transporters play important roles in supplying nutrients to cells. In our current study, we investigated the expression of LAT1 and measured the amino acid uptake in ameloblast cultures to further elucidate the roles of this transporter during the differentiation of these cells. RT-PCR, observations of cell morphology, Alizaline red-S staining, and uptake analyses were performed following the experimental induction of differentiation in the cultures. LAT1 mRNA was detectable and found to gradually increase over time whereas LAT2 mRNA was not evident in the ameloblast cultures. Transcripts of 4F2hc, a cofactor of LAT1 and LAT2, were also found to be expressed in ameloblast cultures and increase with time. Amelogenin mRNA was expressed in the early stage ameloblast cultures. L-leucine uptake was observed to increase over 14 days of growth in culture. Our data suggest that LAT1 has a key role in the differentiation of ameloblasts and in providing these cells with neutral amino acids, including several essential amino acids.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Bei M / 2004 / Msx2 controls ameloblast terminal differentiation / Dev Dyn 231 : 758 ~ 765
Bosshardt DD / 2004 / Hertwig's epithelial root sheath, enamel matrix proteins, and initiation of cementogenesis in porcine teeth / J Clin Periodontol 31 : 184 ~ 192
Chien HH / 1999 / Expression of TGF-beta isoforms and their receptors during mineralized nodule formation by rat periodontal ligament cells in vitro / J Periodontal Res 34 :
Christensen HN / 1990 / Role of amino acid transport and countertransport in nutrition and metabolism / Physiol Rev 70 : 43 ~ 77
D'Souza RN / 1997 / Gene expression patterns of murine dentin matrix protein 1 (Dmp1) and dentin sialophosphoprotein(DSPP) suggest distinct developmental functions in vivo /
Bosshardt DD / 2004 / Hertwig's epithelial root sheath, enamel matrix proteins, and initiation of cementogenesis in porcine teeth / J Clin Periodontol 31 : 184 ~ 192
Chien HH / 1999 / Expression of TGF-beta isoforms and their receptors during mineralized nodule formation by rat periodontal ligament cells in vitro / J Periodontal Res 34 :
Christensen HN / 1990 / Role of amino acid transport and countertransport in nutrition and metabolism / Physiol Rev 70 : 43 ~ 77
D'Souza RN / 1997 / Gene expression patterns of murine dentin matrix protein 1 (Dmp1) and dentin sialophosphoprotein(DSPP) suggest distinct developmental functions in vivo /
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
사람 골육종 세포 Saos2에서 아미노산 수송계 L의 발현 및 기능적 특성
대한구강악안면외과학회지
2006 .01
-
상처치유 과정에서 아미노산 수송계 L의 발현
해부·생물인류학
2006 .03
-
심정격(心正格) 혈위(穴位)에 시술한 침자(鍼刺)와 침습(侵襲)및 비침습(非侵襲) 레이저침요법(鍼療法)이 뇌허혈(腦虛血)에 미치는 영향(影響)에 대한 비교(比較) 연구(硏究)
Korean Journal of Acupuncture
2010 .01
-
Reabsorption of Neutral Amino Acids Mediated by Amino Acid Transporter LAT2 and TAT1 in The Basolateral Membrane of Proximal Tubule
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2005 .01
-
Potential Biomarker of L-type Amino Acid Transporter 1 in Breast Cancer Progression
Nuclear medicine and molecular imaging : NMMI
2011 .01
-
Graves 병(病)에 있어 Long-Acting Thyroid Stimulator(LATS)에 관(關)한 연구(硏究)
대한핵의학회지
1973 .01
-
레이저침에 활용되는 830 nm, 905 nm 레이저의 안전성 연구
Korean Journal of Acupuncture
2012 .01
-
Educational Program of Laboratory Animal Facilities for AV & LAT
한국실험동물학회 학술발표대회 논문집
2015 .08
-
Gene Expression Profiles in T24 Human Bladder Carcinoma Cells by Inhibiting an L-type Amino Acid Transporter, LAT1
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2007 .01
-
Hypermethylation of Promoter Region of LATS1 - a CDK Interacting Protein in Oral Squamous Cell Carcinomas - a Pilot Study in India
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Osterix is Required for Both Ameloblasts and Odontoblasts Maturation and Tooth Development
대한치과재료학회 학술대회
2012 .04
-
법랑모세포 분화와 성숙과정에서 OD314의 발현
Restorative Dentistry and Endodontics
2005 .01
-
Foot Deformity in Charcot Marie Tooth Disease According to Disease Severity
Annals of Rehabilitation Medicine
2011 .01
-
The uptake of basic amino acids into fibroblasts was enhanced by PCA.
대한화장품학회 학술대회
2003 .01
-
L-Type Amino Acid Transporters As Targets For Cancer Diagnosis And Therapeutics
대한약학회 학술대회
2004 .01
-
생쥐의 난포발달과정에 따른 Large Tumor Suppressor 2(lats2) 및 그와 관련된 유전자들의 발현 양상에 관한 연구
대한생식의학회 학술대회
2004 .01
-
Long Acting Thyroid Stimulator(LATS)의 생물학적(生物學的) 검사(檢査)(예보)(努豫)
대한핵의학회 학술대회
1972 .01
-
토끼간에서의 아미노산 이용에 관한 실험적 연구
Annals of Surgical Treatment and Research
1990 .11
-
Graves병(病)에 있어서 Long-Acting Thyroid Stimulator(LATS)의 생물학적(生物學的) 검사(檢査)
대한핵의학회 학술대회
1973 .01
-
흰쥐 절치의 법랑질형성과 법랑모세포 변환주기에 불소가 미치는 영향
치위생과학회지
2008 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0