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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
대한감염학회 Infection and Chemotherapy Infection and Chemotherapy 제41권 제5호
발행연도
2009.1
수록면
272 - 278 (7page)

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Background:Recently, the incidence of hepatitis A has increased in Korea and an outbreak among healthcare workers (HCWs) has also been reported. This study was performed to evaluate the seroepidemiology of hepatitis A among HCWs and their response to vaccination recommendation at a Korean hospital. Materials and Methods:HCWs aged 20–39 years were tested for IgG antibodies against hepatitis A virus (HAV) using ARCHITECT HAVAb-IgG (Abbott Diagnostics Division, Wiesbaden, Germany) during July, 2008. Vaccination was recommended for the seronegative HCWs. Data on age, sex, place of birth, number of siblings, number of children, travel history to endemic areas, occupations, and vaccination history were collected. Statistical analyses were conducted to identify variables related to HAV seropositivity. Results:Among a total of 391 HCWs enrolled, 75 (19%) were males and 316 (81%) were females. The percentages of HCWs aged 20 to 24 years, 25 to 29 years, 30 to 34 years, and 35 to 39 years were 23%, 48%, 17%, and 12%, respectively. The study population comprised of physicians (11%), nurses (62%), nurse aides (5%), paramedical technicians (13%), and administrative staff (9%). Seropositivity for HAV significantly increased with age (P< 0.05):1.1% for 20–24, 8.6% for 25–29, 35.8% for 30–34, and 60.9% for 35–39 years-of-age. Multivariate analysis revealed that HAV seroprevalence correlated significantly with age, HCWs born in the non-metropolitan areas, and having ≥ 3 children (P<0.05). The types of work the HCWs do at the hospital were not significantly associated with HAV seropositivity in multivariate analyses. Of a total of 322 seronegative HCWs, 121 (38%) were not vaccinated in spite of recommendation. The reasons for non-compliance were lack of understanding on the necessity of vaccination (39%), lack of time (26%), expensive costs (16%), fear of injection (15%), and some other reasons including pregnancy (4%). Conclusions:Since the seropositivity for HAV is low, vaccination against Hepatitis A should be considered for all HCWs aged 20-39 years in Korea. Education on the necessity of vaccination is warranted to increase compliance.
#Hepatitis A #Healthcare worker #Seroepidemiology #Vaccination

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참고문헌 (27)

참고문헌 신청
Bell BP / 1998 / The diverse patterns of hepatitis A epidemiology in the United States-implications for vaccination strategies / J Infect Dis 178 : 1579 ~ 1584 google schola Brundage SC / 2006 / / American Family Physician 73 : 2162 ~ 2168 google schola Chodick G / 2003 / Hepatitis A virus seropositivity among hospital and community healthcare workers in Israel-the role of occupation, demography and socioeconomic background google schola Chodick G / 2006 / The risk of hepatitis A infection among health care workers: a review of reported outbreaks and sero-epidemiologic studies / J Hosp Infect 62 : 414 ~ 420 google schola Clemens R / 1995 / Clinical experience with an inactivated hepatitis A vaccine / J Infect google schola

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